The Role of Colour Doppler Imaging in the Diagnosis of Poly Cystic Ovarian . Syndrome: Colour Doppler Imaging in PCOS

Areeba  Aslam; Syyeda  Khadija; Aneeqa  Aslam; Sadia  Shaukat; Ayesha Irshad; Swera Tariq

doi:10.54393/pbmj.v5i2.184

Authors

Areeba Aslam University Institute of Radiological Sciences and Medical Imaging Technology, TheUniversity of Lahore, Pakistan
Syyeda Khadija UniversityInstitute of Radiological sciences and Medical Imaging Technology, TheUniversity of Lahore, Pakistan
Aneeqa Aslam Services Institute of Medical Sciences, Lahore, Pakistan
Sadia Shaukat Rawalpindi Medical University
Ayesha Irshad University Institute of Radiological sciences and Medical Imaging Technology, TheUniversity of Lahore, Pakistan
Swera Tariq University Institute of Radiological sciences and Medical Imaging Technology, TheUniversity of Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i2.184

Keywords:

PCOS, pulsatility index, resistivity index, vascularization index,

Abstract

PCOS(Poly Cystic Ovarian Syndrome) is a hormonal disorder that affects women during their reproductive years (18-30year ).It is a condition that affects ovulation and the ovaries.Many fluid-filled sacs develop inside the ovaries in PCOS.These are follicles,each of which contains an immature egg.The egg is never mature enough to cause ovulation to occur. Important alterations in ovarian vascularization at the level of introvarian arteries occur in PCOS patients. Objective: Is colour Doppler ultrasonography is helpful in evaluation of PCOS. Method: An electronic database search with data range from 1999-2021 was performed(Science Direct, Google Scholar, PubMed, Springer).28 articles were found.All studies fully available evaluating PCOS ondoppler ultrasound. Results: Performance of Doppler ultrasound diagnosis was evaluated. PCOS patients had decreased ovarian artery pulsatility index (PI), resistance index (RI), and SD ratios and increased uterine artery pulsatility index (PI), resistance index (RI), and SD ratios. Conclusion: It is concluded that lowest ovarian stromal resistance levels were found in the patients than the controls.

References

Polson DW, Adams J, Wadsworth J, Franks S. 1988. Polycystic ovaries--a common finding in normal women,journal national library of medicine (8590):870-2 doi: 10.1016/s0140-6736(88)91612-1.

Cesare Battaglia, Paolo G. Artini, Gerardo D'Ambrogio, Alessandro D. Genazzani, Andrea R. Genazzani, The role of color doppler imaging in the diagnosis of polycystic ovary syndrome, American Journal of Obstetrics and Gynecology, Volume 172, Issue 1, Part 1,1995, Pages 108-113,https://doi.org/10.1016/0002-9378(95)90094-2

Zaidi J, Jacobs H, Campbell S, et al. Blood flow changes in the ovarian and uterine arteries in women with polycystic ovary syndrome who respond to clomiphene citrate: correlation with serum hormone concentrations. Ultrasound Obstetric Gynecology1998;12:188. https://doi.org/10.1046/j.1469-0705.1998.12030188.x

EnricoCarmina, Rogerio A. Lobo, Polycystic Ovary Syndrome (PCOS): Arguably the Most Common Endocrinopathy Is Associated with Significant Morbidity in Women, The Journal of Clinical Endocrinology & Metabolism, Volume 84, Issue 6, 1 June 1999, Pages 1897–1899, https://doi.org/10.1210/jcem.84.6.5803

Helvaci, N, Yildiz, BO. The impact of ageing and menopause in women with polycystic ovary syndrome. The journal l of Clin Endocrinol. 2021; 1- 12.https://doi.org/10.1111/cen.14558

Hsien-An Pan, Meng-Hsing Wu, Yueh-Chin Cheng, Chin-Hsien Li, Fong-Ming Chang, Quantification of Doppler signal in polycystic ovary syndrome using three-dimensional power Doppler ultrasonography: a possible new marker for diagnosis, the journal of Human Reproduction, Volume 17, Issue 1, January 2002, Pages 201–206 https://doi.org/10.1093/humrep/17.1.201

Yedla M. Mala, Sharda B. Ghosh, RevaTripathi, Three-dimensional power Doppler imaging in the diagnosis of polycystic ovary syndrome, International Journal of Gynecology & Obstetrics, Volume 105, Issue 1, 2009, Pages 36-38, ISSN 0020-7292https://doi.org/10.1016/j.ijgo.2008.11.042

Özkan, S., Vural, B., Çalışkan, E., Bodur, H., Türköz, E. and Vural, F. (2007), Color dopplersonographic analysis of uterine and ovarian artery blood flow in women with polycystic ovary syndrome. J. Clin. Ultrasound, 35: 305-313. DOI: 10.1002/jcu.20358

ZeinaHaoula, RutaDeshpande, KannamannadiarJayaprakasan& Nick Raine-Fenning (2012) Doppler imaging in the diagnosis of ovarian disease, Expert Opinion on Medical Diagnostics, 6:1, 59-73, https://doi.org/10.1517/17530059.2012.642366

Zafar, U., Memon, Z., Moin, K., Agha, S., Hassan, J. A., &Zehra, D. (2019). Prevalence of PCOS with Associated Symptoms and Complications at Tertiary Care Hospital of Karachi. Journal of Advances in Medicine and Medical Research, 30(4), 1-9. DOI: 10.9734/JAMMR/2019/v30i430190

Seema Patel,Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy, The Journal of Steroid Biochemistry and Molecular Biology, Volume 182, 2018, Pages 27-36, S LinTan, J Zaidi, H S Jacobs, Relationship of ovarian stromal volume to serum androgen concentrations DOI: 10.1016/j.jsbmb.2018.04.008

Clayton, R.N., Ogden, V., Hodgkinson, J., Worswick, L., Rodin, D.A., Dyer, S. and Meade, T.W. (1992), How common are polycystic ovaries in normal women and what is their significance for the fertility of the population?. Clinical Endocrinology, 37: 127-134.https://doi.org/10.1111/j.1365-2265.1992.tb02296.x

A AKyei-Mensah, Relationship of ovarian stromal volume to serum androgen concentrations in patients with polycystic ovary syndrome., Human Reproduction, Volume 13, Issue 6, Jun 1998, Pages 1437–1441, https://doi.org/10.1093/humrep/13.6.1437

Battaglia, C., Battaglia, B., Morotti, E., Paradisi, R., Zanetti, I., Meriggiola, M.C. and Venturoli, S. (2012), Two- and Three-Dimensional Sonographic and Color Doppler Techniques for Diagnosis of Polycystic Ovary Syndrome. Journal of Ultrasound in Medicine, 31: 1015-1024.https://doi.org/10.7863/jum.2012.31.7.1015

• 15. . Adams J, Franks S, Polson DW, Mason HD, Abdulwahid N, Tucker M, Morris DV, Price J, Jacobs HS. Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone. Lancet 1985;2:1375–8DOI: 10.1016/s0140-6736(85)92552-8

. Takahashi K, Eda Y, Abu-Musa A, Okada S, Yoshino K, Kitao M. Transvaginal ultrasound imaging, histopathology and endocrinopathy in patients with polycystic ovarian syndrome. Hum Reprod 1994;7:1231–1236https://doi.org/10.1093/oxfordjournals.humrep.a138684

• 17. Matsunaga I, Hata T, Kitao M. Ultrasonographic identification of polycystic ovary. Asia–Oceania J ObstetGynaecol 1985;11:227–32 DOI: 10.1111/j.1447-0756.1985.tb00738.x

Goswamy RK, Steptoe P. Doppler ultrasound studies of the uterine artery in spontaneous ovarian cycles. Hum Reprod PubMed | CAS | Web of Science® Times Cited: 123 1988;3:721-726.https://doi.org/10.1093/oxfordjournals.humrep.a136772

Dr. Sonia Garg, Dr. Meet Kamal Singh Wadi, Dr. BharatdeepGarg. Color Doppler as diagnostic criteria in polycystic ovarian syndrome (PCOS).Int J ClinObstetGynaecol 2021;5(3):08-11. DOI:10.33545/gynae.2021.v5.i3a.896

Khalaf, IsraaZaidan, and SarabSalihJasim. "ASSESSMENT OF INTRAOVARIAN ARTERIAL DOPPLER ULTRASOUND OF POLYCYSTIC OVARIAN SYNDROME." Turkish Journal of Physiotherapy and Rehabilitation 32: 3.DOI: 321/32-1-1396

Asma, B., Asma, T., &Atiq-ur-R. (2016). Diagnosis of PCOS on Doppler based Resistive Index and Pulsatility Index. JRMC 2016; 20(4), 305-8.2.DOI;32-1-1396

Jamal AF, Ismael RA. Ultrasonographic prevalence of polycystic ovarian morphology among women of reproductive age group.Zanco J Med Sci. 2019 Apr 23;23(1):57-65https://doi.org/10.15218/zjms.2019.008

• 23. Loverro G, Vicino M, Lorusso F, Vimercati A, Greco P, Selvaggi L. Polycystic ovary syndrome: relationship between insulin sensitivity, sex hormone levels and ovarian stromal blood flow. GynecolEndocrinol. 2001;15(2):142-149DOI: 10.1080/gye.15.2.142.149

Heba I Ali, Momena E Elsadawy, Nivan H Khater. Ultrasound assessment of polycystic ovaries: Ovarian volume and morphology; which is more accurate in making the diagnosis?!,.The Egyptian Journal of Radiology and Nuclear Medicine 2016; 47(1):347-50, http://dx.doi.org/10.1016/j.ejrnm.2015.10.002

OzhanOzdemir, Mustafa Erkan Sari, DilekKalkan, EsraMeltemKoc, SeydaOzdemir&CemalResatAtalay (2015) Comprasion of ovarian stromal blood flow measured by color Doppler ultrasonography in polycystic ovary syndrome patients and healthy women with ultrasonographic evidence of polycystic, Gynecological Endocrinology, 31:4, 322-326, DOI: 10.3109/09513590.2014.995617

:Dwivedi S, Ujjaliya MK, Kaushik A. Assessment of the Best Predictor for Diagnosis of Polycystic Ovarian Disease in Color Doppler Study of Ovarian Artery. Int J Sci Stud 2019;6(12):154-162DOI: 2190

Lim, S.S., Davies, M.J., Norman, R.J. and Moran, L.J., 2012. Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis. Human reproduction update, 18(6), pp.618-637. , https://doi.org/10.1093/humupd/dms030