Role of ultrasonography in the diagnosis of dengue fever : Ultrasonography in The Diagnosis of Dengue Fever

Nimra  Manzoor; Syed Muhammad Yousaf  Farooq; Syeda Khadija tul  Sughra; Muhmmad Irshad  Siddiqi; Sukaina  Arooj; Ayesha  Ishfaq; Syed Amir  Gilani; Syed Zain ul  Abidin

doi:10.54393/pbmj.v5i1.245

Authors

Nimra Manzoor University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore.
Syed Muhammad Yousaf Farooq University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore.
Syeda Khadija tul Sughra University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore.
Muhmmad Irshad Siddiqi University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore
Sukaina Arooj University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore.
Ayesha Ishfaq University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore
Syed Amir Gilani University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore.
Syed Zain ul Abidin University institute of radiological sciences & medical imaging technology, Faculty of Allied Health Sciences, The University of Lahore

DOI:

https://doi.org/10.54393/pbmj.v5i1.245

Keywords:

Dengue Haemorrhagic Fever, Plasma Leakage triad, Gallbladder wall thickening, pleural effusion, Ascites, Ultrasound.

Abstract

The purpose of this article is to review the literature and outlining the role of abdominal and chest ultrasonography in the diagnosis and as a predictor of severity of dengue fever. Methods: Standard medical electronic databases were searched and relevant articles were used to present the conclusive outcomes. Results: Eighteen studies on 2601 patients undergoing chest and abdominal ultrasonography fulfilled the inclusion criteria. The incidence of plasma leakage triad such as pleural effusion, ascites and gallbladder wall thickening was 44.98 %, 39.44 % and 61.89 % respectively. Other ultrasonic findings included Hepatomegaly, splenomegaly and pericardial effusion. Conclusion: In patients with suspected dengue fever and dengue haemorrhagic fever, the abdominal and chest ultrasonography, although nonspecific, may be a relevant ancillary tool for the early diagnosis of microvasculature hyper-permeability in addition to a tool used for the prediction of disease severity identifying mild and severe cases of DF. Furthermore, ultrasonography may also be used for the differential diagnosis of other febrile conditions affecting both pediatric and adult population.

References

-Cleland JB, Bradley B, McDonald W: On the Transmission of Australian Dengue by the

Mosquito Stegomyia fasciata. Med J Aust. 1916; 2(10): 179-184.

https://doi.org/10.5694/j.1326-5377.1916.tb117290.x

Chandler AG, Rice L: Observations on the etiology of dengue fever. Am J Trop Med Hyg. 1923; s1-3(3): 233-262.

https://doi.org/10.4269/ajtmh.1923.s1-3.233

Siler JF, Hall MW, Hitchens AP: Dengue: Its history, epidemiology, mechanism of transmission, etiology, clinical manifestations, immunity, and prevention. The Philippine Journal of Science. 1926; 29: 1-304.

Simmons JS, St John JH, Reynolds FHK: Experimental Studies of Dengue. Philipp J Sci. 1931; 44(1-2): 1-252.

Snijders EP, Dinger EJ, Schuffner WAP: On the transmission of dengue in Sumatra. Am J Trop Med Hyg. 1931; s1-11(3): 171-197.

https://doi.org/10.4269/ajtmh.1931.s1-11.171

Sabin AB, Schlesinger RW: Production of immunity to dengue with virus modified by propagation in mice. Science. 1945; 101(2634): 640-2.

https://doi.org/10.1126/science.101.2634.640

Kimura R, Hotta S: On the inoculation of dengue virus into mice. Nippon Igaku. 1944; 3379: 629-633.

Dorrance WR, Frankel JW, Gordon I, et al.: Clinical and serologic response of man to immunization with attenuated dengue and yellow fever viruses. J Immunol. 1956; 77(5): 352-64.

Wisseman CL Jr, Sweet BH, Rosenzweig EC, et al.: Attenuated Living Type 1 Dengue Vaccines. Am J Trop Med Hyg. 1963; 12: 620-623.

https://doi.org/10.4269/ajtmh.1963.12.620

Quintos FN, Lim LE: Philippine hemorrhagic fever. St Tomas J Med. 1956; 11: 319-328.

Hammon WM, Rudnick A, Sather GE: Viruses associated with epidemic hemorrhagic fevers of the Philippines and Thailand. Science. 1960; 131(3407): 1102-3.

https://doi.org/10.1126/science.131.3407.1102

Cohen SN, Halstead SB: Shock associated with dengue infection. I. Clinical and physiologic manifestations of dengue hemorrhagic fever in Thailand, 1964. J Pediatr. 1966; 68(3): 448-56.

https://doi.org/10.1016/S0022-3476(66)80249-4

Weiss HJ, Halstead SB: Studies of hemostasis in Thai hemorrhagic fever. J Pediatr. 1965; 66(5): 918-26.

https://doi.org/10.1016/S0022-3476(65)80068-3

Pathogenetic mechanisms in dengue haemorrhagic fever: report of an international collaborative study. Bull World Health Organ. 1973; 48(1): 117-33.

Bokisch VA, Top FH Jr, Russell PK, et al.: The potential pathogenic role of complement in dengue hemorrhagic shock syndrome. N Engl J Med. 1973; 289(19): 996-1000.

https://doi.org/10.1056/NEJM197311082891902

Halstead SB, Cohen SN: Dengue Hemorrhagic Fever at 60 Years: Early Evolution of Concepts of Causation and Treatment. MicrobiolMolBiol Rev. 2015; 79(3): 281-91.

https://doi.org/10.1128/MMBR.00009-15

Nimmannitya S, Halstead SB, Cohen SN, et al.: Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever. Am J Trop Med Hyg. 1969; 18(6): 954-71.

https://doi.org/10.4269/ajtmh.1969.18.954

Halstead SB. Pathogenesis of Degue: Dawn of a new era. F100 Faculty Review 2015: 1353 (doi: 10.12688/f1000research.7024.1

https://doi.org/10.12688/f1000research.7024.1

19-Tang KF, Ooi EE. Diagnosis of Dengue: an update. Expert Review. Anti Infect. Ther. 2012; 10 (8): 1098-907.

https://doi.org/10.1586/eri.12.76

Oliveira RVB, Rios LTM, Branco MRFC, Braga Júnior LL, Nascimento JMS, Silva GF,

Bandeira KP. Usefulness of ultrasonographyin children with suspected dengue hemorrhagic

fever: a literature review. Radiol Bras. 2010; 43(6): 401-407.

https://doi.org/10.1590/S0100-39842010000600013

Vabo KA, Torres Neto G, Santos AASMD, et al. Achados ultra-sonográficosabdominaisem

pacientes com dengue. Radiol Bras. 2004;37:159-62.

https://doi.org/10.1590/S0100-39842004000300004

Setiawan MW, Samsi TK, Wulur H, et al. Dengue haemorrhagic fever: ultrasound as an aid to

predict the severity of the disease. PediatrRadiol. 1998;28:1-4.

Srikiatkhachorn A, Krautrachue A, Ratanaprakarn W, et al. Natural history of plasma leakage

in dengue hemorrhagic fever: a serial ultrasonographic study. Pediatr Infect Dis J.

;26:283-90.

Thulkar S, Sharma S, Srivastava DN, et al. Sonographic findings in grade III dengue

haemorrhagic fever in adults. J Clin Ultrasound. 2000;28:34-7.

https://doi.org/10.1002/(SICI)1097-0096(200001)28:1<34::AID-JCU5>3.0.CO;2-D

Wu KL, Changchien CS, Kuo CH, et al. Early abdominal sonographic findings in patients with

dengue fever. J Clin Ultrasound. 2004;32:386-8.

https://doi.org/10.1002/jcu.20060

Venkata Sai PM, Dev B, Krishnan R. Role of ultrasound in dengue fever. Br J Radiol. 2005;78:

https://doi.org/10.1259/bjr/54704044

-8.

Balasubramanian S, Janakiraman L, Kumar SS, et al. A reappraisal of the criteria to diagnose

plasma leakage in dengue hemorrhagic fever. Indian Pediatr. 2006;43:334-9.

Firmida MC. Derrame pleural nacriança com dengue. Acta Scientiae Medica. 2008;1:35 43.

Brasil. Ministério da Saúde. Secretaria de VigilânciaemSaúde. Dengue: diagnóstico e manejoclínico - adulto e criança. 3ª ed. Brasília, DF: Ministério da Saúde; 2007.

Pelupessy JM, Allo ER, Jota S. Pericardial effusionin dengue haemorrhagic fever. Paediatr

Indones. 1989;29:72-5.

https://doi.org/10.1016/S0160-3450(15)31755-4

Quiroz-Moreno R, Méndez GF, Ovando-Rivera KM. Utilidadclínica del ultrasonidoen la identificación de dengue hemorrágico. Rev Med Inst Mex Seguro Soc. 2006;44:243-8.

Setiawan MW, Samsi TK, Pool TN, et al. Gallbladder wall thickening in dengue haemorrhagic fever: an ultrasonographic study. J Clin Ultrasound. 1995;23:357-62.

https://doi.org/10.1002/jcu.1870230605

Teefey SA, Baron RL, Bigler SA. Sonography of the gallbladder: significance of striated (layered) thickening of the gallbladder wall. AJR Am J Roentgenol. 1991;156:945-7.

https://doi.org/10.2214/ajr.156.5.2017956

Pramuljo HS, Harun SR. Ultrasound findings in dengue haemorrhagic fever. PediatrRadiol. 1991; 21:100-2.

https://doi.org/10.1007/BF02015615

Gupta S, Singh SK, Taneja V, et al. Gall bladder wall edema in serology proven pediatric

dengue hemorrhagic fever: a useful diagnostic finding which may help in prognostication. J Trop Pediatr. 2000;46:179-81.

https://doi.org/10.1093/tropej/46.3.179-a

Sehgal A, Gupta S, Tyagi V, et al. Gall bladder wall edema is not pathogenic of dengue

infection. J Trop Pediatr. 2002;48:315-6.

https://doi.org/10.1093/tropej/48.5.315

Colbert JA, Gordon A, Roxelin R, et al. Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients. Pediatr Infect Dis J. 2007;26:850-2.

https://doi.org/10.1097/INF.0b013e3180619692

Motla M, Manaktala S, Gupta V, Aggarwal M, Bhoi SK, Aggarwal P, Goel A. Sonographic evidence of ascites, pleura-pericardial effusion and gallbladder wall edema for dengue fever.

Prehosp Disaster Med. 2011; 26: 335-41.

Venkata Sai PM, Dev B, Krishnan R. Role of ultrasound in dengue fever. Br J Radiol. 2005;

https://doi.org/10.1259/bjr/54704044

: 416-8.

Khurram M, Qayyum W, Umar M, Jawad M, Mumtaz S, BushraKhaar HT.

Ultrasonographic pattern of plasma leak in dengue haemorrhagic fever. J Pak Med Assoc.

; 66: 260-4