Analgesic Efficacy of Ropivacaine Infiltration in Puncture Site of Mini Percutaneoius Nephrolithotomy Tract

Ropivacaine Infiltration in Mini Percutaneous Nephrolithotomy Tract

Authors

  • Asif Khan Department of Urology, Saidu Teaching Hospital, Swat
  • Tauheed Fareed Department of Urology, Peshawar Institute of Medical Sciences Hayatabad, Peshawar
  • Sayed Ghaffar Shah Department of Pediatric Urology, Children Hospital, Lahore
  • Muhammad Shoaib Department of Urology, PAF hospital, Islamabad
  • Qudrat Ullah Department of Urology, Institute of Kidney Diseases, Hayatabad, Peshawar
  • Naqib Ullah Department of Urology, Rehman Medical Institute, Peshawar

DOI:

https://doi.org/10.54393/pbmj.v5i1.334

Keywords:

Percutaneous Nephrolithotomy, Ropivacaine Infiltration, Post-Operative Pain

Abstract

To compare the mean postoperative pain score in patients with ropivacaine infiltration in the access tract with placebo in patients undergoing mini percutaneous nephrolithotomy. Methods: Total 82 adult patients of either gender undergoing mini percutaneous nephrolithotomy, between 9 and 63 years of age were included in the study. The patients were randomly allocated into two groups by lottery method. Patients in group A were given 20ml of 0.25% ropivacaine in the access tract while patients in group B were given 20ml of normal saline as placebo at the beginning of surgery at the nephrostomy site. Post operatively all patients were carefully followed at 2, 4 and finally at 6 hours. All patients were examined to determine the pain scores at the mini PCNL    puncture site using visual analogue scale. Results: The mean age of patients in group A was 40.60 ± 11.62 years and in group B was 40.26 ± 13.15 years. Out of 82 patients 43 (51.43%) patents were male and 39 (48.57%) were female with male to female ratio of 1.1:1. Mean postoperative pain score in patients with preoperative ropivacaine infiltration (group A) of nephrostomy tract was 3.2 ± 1.2 and in placebo (group B) was 5.60 ± 1.64 with p-value of 0.0001. Conclusion: This study concluded that mean postoperative pain score of  ropivacaine infiltration in the PCNL tract  is less than placebo in patients undergoing mini percutaneous nephrolithotomy.

References

Pearle MS, Lotan Y. Urinary lithiasis: etiology, epidemiology, and pathogenesis. In: Wein AJ, Kavoussi LR, Norvick AC, Partin AW, Peters CA, editors. Campbell's Urology. 10th ed. Philadelphia: Elsevier Saunders; 2012. p. 1257-86.

Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int. 2003;63:1817-23.

https://doi.org/10.1046/j.1523-1755.2003.00917.x

.Ferakis N, Stavropoulos M. Mini percutaneous nephrolithotomy in the treatment of renal and upper ureteral stones: Lessons learned from a review of the literature. Urol Ann. 2015;7(2):141-8.

https://doi.org/10.4103/0974-7796.152927

. Prezioso D, Di Martino M, Galasso R, Iapicca G. Laboratory assessment. Urol Int. 2007;79(Suppl 1):20-5.

https://doi.org/10.1159/000104437

Skolarikos A, Straub M, Knoll T, Sarica K, Seitz C, Petřík A, et al. Metabolic Evaluation and Recurrence Prevention for Urinary Stone Patients: EAU Guidelines. Eur Urol. 2015 Apr;67(4):750-63.

https://doi.org/10.1016/j.eururo.2014.10.029

.Michel MS, Trojan L, Rassweiler JJ. Complications in percutaneous nephrolithotomy. Eur Urol. 2007;51:899-906.

https://doi.org/10.1016/j.eururo.2006.10.020

Patel SR, Nakada SY, The modern history and evolution of percutaneous nephrolithotomy, J Endourol. 2015 Feb;29(2):153-7

https://doi.org/10.1089/end.2014.0287

Ozgor F, Kucuktopcu O, Ucpinar B, Sarilar O, Erbin A, Yanaral F, etal. The effects of previous open renal stone surgery types on PNL outcomes. Can Urol Assoc J. 2016;10(7-8)

https://doi.org/10.5489/cuaj.3687

.Lee LC, Violette PD, Tailly T, Dave S, Denstedt JD, Razvi H. A comparison of outcomes after percutaneous nephrolithotomy in children and adults: a matched cohort study. J Pediatr Urol. 2015 ;11(5):250-6.

https://doi.org/10.1016/j.jpurol.2015.04.002

.

Shah K, Agrawal MS, Mishra DK. Superperc: A new technique in minimally-invasive percutaneous nephrolithotomy. Indian J Urol. 2017;33(1):48-52.

.Choi SW, Cho SJ, Moon HW, Lee KW, Lee SH, Hong SH, et al. Effect of Intercostal Nerve Block and Nephrostomy Tract Infiltration With Ropivacaine on Postoperative Pain Control After Tubeless Percutaneous Nephrolithotomy: a prospective, randomized, and case-controlled trial. Urology. 2017;4295(17)31312-2.

Luo J, Min S. Postoperative pain management in the postanesthesia care unit: an update. J Pain Res. 2017 16;10:2687-98.

https://doi.org/10.2147/JPR.S142889

.Parikh GP, Shah VR, Vora KS, Parikh BK, Modi MP, Kumari P. Ultrasound guided peritubal infiltration of 0.25% Bupivacaine versus 0.25% Ropivacaine for postoperative pain relief after percutaneous nephrolithotomy: A prospective double blind randomized study. Indian J Anaesth. 2014;58(3):293-7.

https://doi.org/10.4103/0019-5049.135040

Lojanapiwa ation in postoperative pain following percutaneous nephrolithotomy - a prospective randomized controlled study. Int BrazJ Urol. 2015;41(5):945-52.

https://doi.org/10.1590/S1677-5538.IBJU.2014.0471

.Shimazu Y, Shibuya E, Takehana S, Sekiguchi K, Oshima K, Kamata H, etal. Local administration of resveratrol inhibits excitability of nociceptive wide-dynamic range neurons in rat trigeminal spinal nucleus caudalis. Brain Res Bull. 2016;124:262-8.

https://doi.org/10.1016/j.brainresbull.2016.06.001

Bektas F, Eken C, Karadeniz O, Goksu E, Cubuk M, Cete Y. Intravenous paracetamol or morphine for the treatment of renal colic: a randomized, placebo-controlled trial. Ann Emerg Med. 2009;54:568-74.

https://doi.org/10.1016/j.annemergmed.2009.06.501

Memis D, Inal MT, Kavalci G, Sezer A, Sut N. Intravenous paracetamol reduced the use of opioids, extubation time, and opioid-related adverse effects after major surgery in intensive care unit. J Crit Care. 2010;25:458-62.

https://doi.org/10.1016/j.jcrc.2009.12.012

Desai MR, Kukreja RA, Desai MM, Mhaskar SS, Wani KA, Patel SH, et al. A prospective randomized comparison of type of nephrostomy drainage following percutaneous nephrostolithotomy: large bore versus small bore versus tubeless. J Urol. 2004;172:565-7.

https://doi.org/10.1097/01.ju.0000130752.97414.c8

Bellman GC, Davidoff R, Candela J, Gerspach J, Kurtz S, Stout L. Tubeless percutaneous renal surgery. J Urol. 1997;157:1578-82.

https://doi.org/10.1016/S0022-5347(01)64799-2

Kehlet H, Rung GW, Callesen T. Postoperative opioid analgesia: time for a reconsideration?. Journal of clinical anesthesia. 1996 Sep 1;8(6):441-5.

https://doi.org/10.1016/0952-8180(96)00131-6

Papic JC, Finnell SM, Howenstein AM, Breckler F, Leys CM. Postoperative opioid analgesic use after Nuss versus Ravitch pectus excavatum repair. Journal of Pediatric Surgery. 2014 Jun 1;49(6):919-23.

https://doi.org/10.1016/j.jpedsurg.2014.01.025

Gupta A, Bah M. NSAIDs in the treatment of postoperative pain. Current pain and headache reports. 2016 Nov;20(11):1-4.

https://doi.org/10.1007/s11916-016-0591-7

Haleblian GE, Sur RL, Albala DM, Preminger GM. Subcutaneous bupivacaine infiltration and postoperative pain perception after percutaneous nephrolithotomy. J Urol. 2007;178:925-8.

https://doi.org/10.1016/j.juro.2007.05.025

Jonnavithula N, Pisapati MV, Durga P, Krishnamurthy V, Chilumu R, Reddy B. Efficacy of peritubal local anesthetic infiltration in alleviating postoperative pain in percutaneous nephrolithotomy. J Endourol. 2009;23:857-60.

https://doi.org/10.1089/end.2008.0634

Ugras MY, Toprak HI, Gunen H, Yucel A, Gunes A. Instillation of skin, nephrostomy tract, and renal puncture site with ropivacaine decreases pain and improves ventilatory function after percutaneous nephrolithotomy. Journal of endourology. 2007 May 1;21(5):499-503.

https://doi.org/10.1089/end.2006.0335

Dalela D, Goel A, Singh P, Shankhwar SN. Renal capsular block: a novel method for performing percutaneous nephrolithotomy under local anesthesia. Journal of endourology. 2004 Aug 1;18(6):544-6.

https://doi.org/10.1089/end.2004.18.544

Parikh, G.P., Shah, V.R., Modi, M.P. and Chauhan, N.C., 2011. The analgesic efficacy of peritubal infiltration of 0.25% bupivacaine in percutaneous nephrolithotomy-A prospective randomized study. Journal of anaesthesiology, clinical pharmacology, 27(4), p.481.

https://doi.org/10.4103/0970-9185.86591

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Published

2022-01-31
CITATION
DOI: 10.54393/pbmj.v5i1.334
Published: 2022-01-31

How to Cite

Khan, A. ., Fareed, T. ., Shah, S. G. ., Shoaib, M. ., Ullah, Q. ., & Ullah, N. . (2022). Analgesic Efficacy of Ropivacaine Infiltration in Puncture Site of Mini Percutaneoius Nephrolithotomy Tract: Ropivacaine Infiltration in Mini Percutaneous Nephrolithotomy Tract. Pakistan BioMedical Journal, 5(1), 322–326. https://doi.org/10.54393/pbmj.v5i1.334

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