Antimicrobial Susceptibility Pattern of Pseudomonas aeruginosa isolated from Clinical and Environmental Sources in Punjab, Pakistan: Antimicrobial Susceptibility Pattern of Pseudomonas Aeruginosa

Muhammad  Kamran; Muhammad  Adil Choudary; Haroon  Amin; Samra  Asghar; Adeel  Shahid; Saba  Zafar; Hamza  Javed; Muhammad  Hassan Sarfraz; Mohsin  Khurshid

doi:10.54393/pbmj.v5i3.349

Authors

Muhammad Kamran Department of Medical Laboratory Technology, Islamabad Medical & Dental College, Islamabad, Pakistan
Muhammad Adil Choudary Central Park Medical College, Lahore, Pakistan
Haroon Amin Department of Biochemistry, Government College University Faisalabad, Pakistan
Samra Asghar Faculty of Rehabilitation and Allied Health Sciences, Riphah International University Faisalabad, Pakistan
Adeel Shahid Faculty of Rehabilitation and Allied Health Sciences, Riphah International University Faisalabad, Pakistan
Saba Zafar Faculty of Rehabilitation and Allied Health Sciences, Riphah International University Faisalabad, Pakistan
Hamza Javed Department of Microbiology, Government College University Faisalabad, Pakistan
Muhammad Hassan Sarfraz Department of Microbiology, Government College University Faisalabad, Pakistan
Mohsin Khurshid Department of Microbiology, Government College University Faisalabad, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i3.349

Keywords:

Pseudomonas aeruginosa, Antimicrobial Resistance, Cipro

Abstract

The increasing incidence of antimicrobial resistance is a public health concern, and Pseudomonas aeruginosa is known to be resistant to a variety of antibiotics. Antimicrobial resistance and the multiple antibiotic resistance (MAR) index of P. aeruginosa from environmental and clinical sources were studied in the current study. A total of 170 samples were evaluated, with 85 samples each from environmental sources and clinical settings. The isolates were subjected to microbial analysis and antimicrobial sensitivity testing. The findings revealed that 45.88 % (39) of the 85 clinical isolates tested for the presence of P. aeruginosa were positive. In terms of prevalence, there were significant variations (p 0.05) between the clinical samples. Wound samples had the highest isolation rate of 28.2%, while urine samples had the lowest (12.8%). P. aeruginosa was found in 38.8 % (33/85) of the samples isolated from environmental sources. In terms of prevalence, there was a highly significant difference (p 0.01) between the isolates. All of the positive isolates were completely resistant to cefuroxime and amoxicillin (100 %). The majority were also resistant to, cotrimoxazole (82%), nalidixic acid (82%), ciprofloxacin (86%), and tobramycin (69%). There was a substantial variation in the resistance patterns of isolates. The current study demand comprehensive measure to combat antimicrobial resistance in P. aeruginosa.

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