Prevalence of Anemia in Community-Acquired Pneumonia Patients

Anemia Prevalence in Hospitalized Pneumonia Patients

Authors

  • Samina Saeed Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan
  • Muhammad Usman Yaqub Avicenna Medical College and Hospital, Lahore, Pakistan
  • Aysha Ghayyur Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan
  • Shazia Siddique Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan
  • Muhammad Anwar Department of Paediatrics Medicine, Rashid Latif Medical College, Lahore, Pakistan
  • Ayesha Afzal Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v7i04.1088

Keywords:

Anemia, Diabetes Mellitus, Pneumonia, Prevalence

Abstract

The frequency of anemia in intensive care units is well documented. Less is known, however, about the prevalence of anaemia in hospitalised patients with community-acquired pneumonia, which is one of the common reasons for hospitalisation, affecting both healthy and co-morbid individuals and is usually not accompanied with acute blood loss. Objective: To determine the frequency of anemia in patients presenting with pneumonia. Methods: This descriptive cross-sectional study was conducted with pneumonia patients at Department of Medicine Pulmonology in HDU/ICU Jinnah Hospital, Lahore curing thr period of three months. The 345 subjects with mean age 44.4 ± 9.4 (range: 20 – 60) years, male to female ratio 1:1.12, diagnosed with pneumonia underwent assessment of hemoglobin levels at presentation. Relationship between anemia and other co-morbidities has been evaluated that included duration of pneumonia, obesity, diabetes mellitus and hypertension. Results: The mean duration of pneumonia symptoms was 8.7 ± 6.9 (range: 2-25) days whereas the mean hemoglobin concentration was found 12.3 ± 6.9 g/dL ranged from 7.1 –14.6 g/dL. The prevalence of anemia was found to be 37.7% and 215 (62.3%) of the 345 patients have shown normal hemoglobin levels. Female gender, higher age, greater duration of pneumonia symptoms and presence of diabetes mellitus significantly correlated with anemia in pneumonia (p-value < 0.05). Whereas, obesity did not have any significant effects on anemia in pneumonia (p-value > 0.05). Conclusions: Anemia was present in significant number of patients with pneumonia and was associated with female gender, Diabetes ,Hypertension and prolonged duration of pneumonia.

References

Lin CJ, Chang YC, Tsou MT, Chan HL, Chen YJ, Hwang LC et al. Factors associated with hospitalization for community-acquired pneumonia in home health care patients in Taiwan. Aging Clinical and Experimental Research. 2020 Jan; 32: 149-55. doi: 10.1007/s40520-019-01169-8. DOI: https://doi.org/10.1007/s40520-019-01169-8

Alsharkawy AA and Rezk AR. Role of vitamin D, serum zinc, and serum iron deficiency in community-acquired pneumonia in children. Egyptian Pediatric Association Gazette. 2021 Dec; 69: 1-7. doi: 10.1186/s43054-021-00065-z. DOI: https://doi.org/10.1186/s43054-021-00065-z

Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clinical Microbiology and Infection. 2012 Mar; 18(3): 268-81. doi: 10.1111/j.1469-0691.2011.03570.x. DOI: https://doi.org/10.1111/j.1469-0691.2011.03570.x

Doshi SM, Rueda AM, Corrales-Medina VF, Musher DM. Anemia and community-acquired pneumococcal pneumonia. Infection. 2011 Aug; 39: 379-83. doi: 10.1007/s15010-011-0122-8. DOI: https://doi.org/10.1007/s15010-011-0122-8

De Porto AP, Lammers AJ, Bennink RJ, Ten Berge IJ, Speelman P, Hoekstra JB et al. Assessment of splenic function. European Journal of Clinical Microbiology & Infectious Diseases. 2010 Dec; 29: 1465-73. doi: 10.1007/s10096-010-1049-1. DOI: https://doi.org/10.1007/s10096-010-1049-1

Huaman Junco G, La Cruz-Vargas D, Jhony A. Clinical and laboratory factors associated with nosocomial pneumonia in adult patients in the internal medicine department of a national hospital in Peru: A case-control study. Medwave. 2021 Oct; 21(09): e8482. doi: 10.5867/medwave.2021.09.8482. DOI: https://doi.org/10.5867/medwave.2021.09.8482

Enright MC, Day NP, Davies CE, Peacock SJ, Spratt BG. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. Journal of Clinical Microbiology. 2000 Mar; 38(3): 1008-15. doi: 10.1128/JCM.38.3.1008-1015.2000. DOI: https://doi.org/10.1128/JCM.38.3.1008-1015.2000

Han X, He B, Wang F. Mycoplasma pneumonia associated with hemolytic anemia: case report and literature review. Zhonghua jie he he hu xi za zhi= Zhonghua Jiehe he Huxi Zazhi= Chinese Journal of Tuberculosis and Respiratory Diseases. 2011 Nov; 34(11): 832-6.

Ticona JH, Zaccone VM, McFarlane IM. Community-acquired pneumonia: A focused review. American Journal of Medical Case Reports. 2021 Nov; 9(1): 45-52. doi: 10.12691/ajmcr-9-1-12. DOI: https://doi.org/10.12691/ajmcr-9-1-12

Chang IF, Shih WL, Liu YC, Ho TW, Yen TY, Chang HH et al. The association of anemia with the clinical outcomes of community‐acquired pneumonia in children. Pediatric Pulmonology. 2022 Jun; 57(6): 1416-24. doi: 10.1002/ppul.25892. DOI: https://doi.org/10.1002/ppul.25892

Bozza MT and Jeney V. Pro-inflammatory actions of heme and other hemoglobin-derived DAMPs. Frontiers in Immunology. 2020 Jun; 11: 548128. doi: 10.3389/fimmu.2020.01323. DOI: https://doi.org/10.3389/fimmu.2020.01323

Taneri PE, Gómez-Ochoa SA, Llanaj E, Raguindin PF, Rojas LZ, Roa-Díaz ZM et al. Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis. European Journal of Epidemiology. 2020 Aug; 35: 763-73. doi: 10.1007/s10654-020-00678-5. DOI: https://doi.org/10.1007/s10654-020-00678-5

Lee CT, Chen MZ, Yip CY, Yap ES, Lee SY, Merchant RA et al. Prevalence of anemia and its association with frailty, physical function and cognition in community-dwelling older adults: findings from the HOPE study. The Journal of Nutrition, Health and Aging. 2021 May; 25(5): 679-87. doi: 10.1007/s12603-021-1625-3. DOI: https://doi.org/10.1007/s12603-021-1625-3

He Y, Li M, Mai C, Chen L, Zhang X, Zhou J et al. Anemia and low albumin levels are associated with severe community-acquired pneumonia in pregnancy: a case-control study. The Tohoku Journal of Experimental Medicine. 2019 Aug; 248(4): 297-305. doi: 10.1620/tjem.248.297. DOI: https://doi.org/10.1620/tjem.248.297

Falagas ME, Kasiakou SK, Saravolatz LD. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clinical Infectious Diseases. 2005 May; 40(9): 1333-41. doi: 10.1086/429323. DOI: https://doi.org/10.1086/429323

Black S, Kushner I, Samols D. C-reactive protein. Journal of Biological Chemistry. 2004 Nov; 279(47): 48487-90. doi: 10.1074/jbc.R400025200. DOI: https://doi.org/10.1074/jbc.R400025200

Reade MC, Weissfeld L, Angus DC, Kellum JA, Milbrandt EB. The prevalence of anemia and its association with 90-day mortality in hospitalized community-acquired pneumonia. BMC Pulmonary Medicine. 2010 Dec; 10: 1-0. doi: 10.1186/1471-2466-10-15. DOI: https://doi.org/10.1186/1471-2466-10-15

Cheng S, Hou G, Liu Z, Lu Y, Liang S, Cang L, Zhang X, Zou C, Kang J, Chen Y. Risk prediction of in-hospital mortality among patients with type 2 diabetes mellitus and concomitant community-acquired pneumonia. Annals of Palliative Medicine. 2020 Sep; 9(5): 3313-3325. doi:10.21037/apm-20-1489. doi: 10.21037/apm-20-1489. DOI: https://doi.org/10.21037/apm-20-1489

Huang D, He D, Gong L, Wang W, Yang L, Zhang Z et al. Clinical characteristics and risk factors associated with mortality in patients with severe community-acquired pneumonia and type 2 diabetes mellitus. Critical Care. 2021 Dec; 25: 1-4. doi: 10.1186/s13054-021-03841-w. DOI: https://doi.org/10.1186/s13054-021-03841-w

Chisti MJ, Kawser CA, Rahman AS, Shahid AS, Afroze F, Shahunja KM et al. Prevalence and outcome of anemia among children hospitalized for pneumonia and their risk of mortality in a developing country. Scientific Reports. 2022 Jun; 12(1): 10741. doi: 10.1038/s41598-022-14818-2. DOI: https://doi.org/10.1038/s41598-022-14818-2

Downloads

Published

2024-04-30
CITATION
DOI: 10.54393/pbmj.v7i04.1088
Published: 2024-04-30

How to Cite

Saeed, S., Yaqub, M. U., Ghayyur, A., Siddique, S., Anwar, M., & Afzal, A. (2024). Prevalence of Anemia in Community-Acquired Pneumonia Patients: Anemia Prevalence in Hospitalized Pneumonia Patients. Pakistan BioMedical Journal, 7(04), 36–40. https://doi.org/10.54393/pbmj.v7i04.1088

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)