A Comparative Evaluation of Perioperative Analgesic Use in Orthopaedic and General Surgery Departments

Perioperative Analgesic Use in Orthopaedic and General Surgery Departments

Authors

  • . Bayazeed Department of Surgery, Medical Teaching Institution, Mardan Medical Complex, Mardan, Pakistan
  • Zahir Khan Department of Orthopaedic Surgery, Medical Teaching Institution, Mardan Medical Complex, Mardan, Pakistan
  • Mustafa Javaid Department of Internal Medicine, Oxford University Hospitals NHS Foundation Trust, United Kingdom
  • . Rumman Department of Pharmacovigilance Center, Medical Teaching Institution, Mardan Medical Complex, Mardan, Pakistan
  • Muhammad Luqman Department of Pharmacology, Peshawar Medical College, Peshawar, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v9i10.1410

Keywords:

Perioperative Analgesia, Orthopaedic Surgery, General Surgery, Opioids, Multimodal Analgesia, Postoperative Pain

Abstract

The need for perioperative analgesia varies based on surgical specialty, and medication-related risks arise when inappropriate opioids are used. Objective: To compare perioperative analgesic utilization and postoperative pain between orthopaedic and general surgery patients. Methods: This prospective comparative observational study included 266 patients, with 133 each from Orthopaedic and General Surgery departments at Medical Teaching Institution, Mardan Medical Complex (MTI-MMC). Demographic, surgical, analgesic, dose, opioid exposure, and postoperative Numerical Rating Scale (NRS) pain data were collected from medical records. Independent-samples t-test, Mann–Whitney U test, and Chi-square/Fisher’s exact test were used to compare groups. Results: Opioid use was significantly higher in orthopaedics than in general surgery patients (p=0.037), as were opioid exposure (p=0.018) and the number of analgesic classes (p=0.031). Orthopaedic patients had higher NRS pain scores at 2, 6, and 12 hours (p=0.009, 0.014, and 0.025, respectively), while the 24-hour difference was non-significant (p=0.052). Rescue opioid use was also higher in orthopaedics (p=0.048), whereas overall rescue analgesia was not significant (p=0.062). Conclusions: It was concluded that orthopaedic patients had greater perioperative opioid utilization, opioid exposure, postoperative pain scores, and rescue opioid requirements than general surgery patients. These findings highlight differences in analgesic requirements between surgical specialties and support the need for procedure-specific multimodal analgesic strategies with appropriate opioid-sparing approaches to achieve effective pain control while minimizing unnecessary opioid exposure.

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Published

2026-10-31

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Original Article

How to Cite

Bayazeed, ., Khan, Z., Javaid, M., Rumman, ., & Luqman, M. (2026). A Comparative Evaluation of Perioperative Analgesic Use in Orthopaedic and General Surgery Departments: Perioperative Analgesic Use in Orthopaedic and General Surgery Departments. Pakistan BioMedical Journal, 9(10), 10-16. https://doi.org/10.54393/pbmj.v9i10.1410

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