Exploring the Efficacy and Safety of Herbal Remedies for the Management of Sleep Deprivation in Insomnia : Herbal Remedies for the Management of Sleep Deprivation

Nimra Naeem; Muhammad  Bilal; Asra  Abbas; Fatima  Raza

doi:10.54393/pbmj.v6i10.949

Authors

Nimra Naeem University of Management and Technology, Lahore, Pakistan
Muhammad Bilal Department of Anesthesia and ICU, Hameed Latif Hospital, Lahore, Pakistan
Asra Abbas University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
Fatima Raza University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v6i10.949

Keywords:

Insomnia, Sleep Deprivation, Alternative Medicine, Herbal Treatments

Abstract

Insomnia is most common sleep disorder effecting many lives. Various factors contribute in our sleep cycle like stress, daily activity, workload, use of gadgets/ screen time and many more. If your circadian rhythm got disturbed it will affect your sleep cycle. It might lead to many health issues, fatigue, decline in cognitive function. Now a day’s adults along with youth are having insomnia issues due to multiple reasons. If it remains untreated it will affect your quality of life. Since long pharmacological therapies are used that will have negative effect on longer run so herbs like valarine, chamomile and lavenders are now being used because of their sedative properties it acts on nervous system and help to get rid of insomnia. Herbs have gained popularity as its natural and help sleep better.

References

Bolstad CJ, and Nadorff MR. What types of insomnia relate to anxiety and depressive symptoms in late life?. Heliyon. 2020 Nov; 6(11). doi: 10.1016/j.heliyon.2020.e05315. DOI: https://doi.org/10.1016/j.heliyon.2020.e05315

Levenson JC, Kay DB, Buysse DJ. The pathophysiology of insomnia. Chest. 2015 Apr; 147(4): 1179-92. doi: 10.1378/chest.14-1617. DOI: https://doi.org/10.1378/chest.14-1617

Patel RK, Gangwar D, Gupta H, Sharma N, Kumar R. Plants Alkaloids Based Compound as Therapeutic Potential for Neurodegenerative. Journal for Research in Applied Sciences and Biotechnology. 2023 Apr; 2(2): 14-26. doi: 10.55544/jrasb.2.2.3. DOI: https://doi.org/10.55544/jrasb.2.2.3

Krystal AD, Prather AA, Ashbrook LH. The assessment and management of insomnia: an update. World Psychiatry. 2019 Oct; 18(3): 337-52. doi: 10.1002/wps.20674. DOI: https://doi.org/10.1002/wps.20674

Waters F, Chiu VW, Dragovic M, Ree M. Different patterns of treatment response to Cognitive-Behavioural Therapy for Insomnia (CBT-I) in psychosis. Schizophrenia Research. 2020 Jul; 221: 57-62. doi: 10.1016/j.schres.2020.03.054. DOI: https://doi.org/10.1016/j.schres.2020.03.054

Birling Y, Jia M, Li G, Sarris J, Bensoussan A, Zhu X. Zao Ren An Shen for insomnia: a systematic review with meta-analysis. Sleep Medicine. 2020 May; 69: 41-50. doi: 10.1016/j.sleep.2019.12.023. DOI: https://doi.org/10.1016/j.sleep.2019.12.023

Bhaskar S, Hemavathy D, Prasad S. Prevalence of chronic insomnia in adult patients and its correlation with medical comorbidities. Journal of Family Medicine and Primary Care. 2016 Oct; 5(4): 780. doi: 10.4103/2249-4863.201153. DOI: https://doi.org/10.4103/2249-4863.201153

Chaudhry S. Managing insomnia efficiently. IP Journal of Surgery and Allied Sciences. 2020; 2(3): 58-63. doi: 10.18231/j.jsas.2020.008. DOI: https://doi.org/10.18231/j.jsas.2020.008

Kaur H, Spurling BC, Bollu PC. Chronic insomnia. StatPearls Publishing; 2018.

Kay DB, and Buysse DJ. Hyperarousal and beyond: new insights to the pathophysiology of insomnia disorder through functional neuroimaging studies. Brain Sciences. 2017 Feb; 7(3): 23. doi: 10.3390/brainsci7030023. DOI: https://doi.org/10.3390/brainsci7030023

Bollu PC, and Kaur H. Sleep medicine: insomnia and sleep. Missouri Medicine. 2019 Jan; 116(1): 68.

Neubauer DN. Chronic insomnia: current issues. Clinical Cornerstone. 2004 Jan; 6(1): S17-22. doi: 10.1016/S1098-3597(04)80044-9. DOI: https://doi.org/10.1016/S1098-3597(04)80044-9

Umar A, Khan MS, Sehgal SA, Jafar K, Ahmad S, Waheed A, et al. Epidemiological studies of sleep disorder in educational community of Pakistani population, its major risk factors and associated diseases. PloS One. 2022 Apr; 17(4): e0266739. doi: 10.1371/journal.pone.0266739. DOI: https://doi.org/10.1371/journal.pone.0266739

Tiwari S, and Talreja S. Insomnia: A study on sleeping disorder with the reference of ayurvedic herbs. Journal of Pharmaceutical Sciences and Research. 2020 Nov; 12(11): 1375-9.

Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, et al. European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research. 2017 Dec; 26(6): 675-700. doi: 10.1111/jsr.12594. DOI: https://doi.org/10.1111/jsr.12594

Anderson KN. Insomnia and cognitive behavioural therapy—how to assess your patient and why it should be a standard part of care. Journal of Thoracic Disease. 2018 Jan; 10(1): 94. doi: 10.21037/jtd.2018.01.35. DOI: https://doi.org/10.21037/jtd.2018.01.35

Rajendra N, Sandeep B, Gajanan P. Nidranasha (Insomnia) causes, consequences & management an ayurvedic perspective. International Journal of Herbal Medicine. 2013 Sep; 1: 68-72.

Buysse DJ, Rush AJ, Reynolds CF. Clinical management of insomnia disorder. JAMA. 2017 Nov; 318(20): 1973-4. doi: 10.1001/jama.2017.15683. DOI: https://doi.org/10.1001/jama.2017.15683

Chaves PF, Palloma de Almeida SH, Dallazen JL, de Paula Werner MF, Iacomini M, Andreatini R, et al. Chamomile tea: Source of a glucuronoxylan with antinociceptive, sedative and anxiolytic-like effects. International Journal of Biological Macromolecules. 2020 Dec; 164: 1675-82. doi: 10.1016/j.ijbiomac.2020.08.039. DOI: https://doi.org/10.1016/j.ijbiomac.2020.08.039

Taavoni S, Ekbatani N, Kashaniyan M, Haghani H. Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial. Menopause. 2011 Sep; 18(9): 951-5. doi: 10.1097/gme.0b013e31820e9acf. DOI: https://doi.org/10.1097/gme.0b013e31820e9acf

Tammadon MR, Nobahar M, Hydarinia-Naieni Z, Ebrahimian A, Ghorbani R, Vafaei AA. The effects of valerian on sleep quality, depression, and state anxiety in hemodialysis patients: a randomized, double-blind, crossover clinical trial. Oman Medical Journal. 2021 Mar; 36(2): e255. doi: 10.5001/omj.2021.56. DOI: https://doi.org/10.5001/omj.2021.56

Adib-Hajbaghery M, and Mousavi SN. The effects of chamomile extract on sleep quality among elderly people: A clinical trial. Complementary Therapies in Medicine. 2017 Dec; 35: 109-14. doi: 10.1016/j.ctim.2017.09.010. DOI: https://doi.org/10.1016/j.ctim.2017.09.010

Hasan SM. Study on the effect of Chamomile extract on melatonin hormone levels in subjects suffering from insomnia and anxiety. Biomedicine. 2022 Dec; 42(6): 1301-4. doi: 10.51248/. v42i6.2269. DOI: https://doi.org/10.51248/.v42i6.2269

dos Reis Lucena L, dos Santos-Junior JG, Tufik S, Hachul H. Lavender essential oil on postmenopausal women with insomnia: Double-blind randomized trial. Complementary Therapies in Medicine. 2021 Jun; 59: 102726. doi: 10.1016/j.ctim.2021.102726. DOI: https://doi.org/10.1016/j.ctim.2021.102726

Lari ZN, Hajimonfarednejad M, Riasatian M, Abolhassanzadeh Z, Iraji A, Vojoud M, Heydari M, et al. Efficacy of inhaled Lavandula angustifolia Mill. Essential oil on sleep quality, quality of life and metabolic control in patients with diabetes mellitus type II and insomnia. Journal of Ethnopharmacology. 2020 Apr; 251: 112560. doi: 10.1016/j.jep.2020.112560. DOI: https://doi.org/10.1016/j.jep.2020.112560

Martínez-Ávila GC, Aguilar-Zarate P, Rojas R. Currently applied extraction processes for secondary metabolites from Lippia turbinata and Turnera diffusa and future perspectives. Separations. 2021 Sep; 8(9): 158. doi: 10.3390/separations8090158. DOI: https://doi.org/10.3390/separations8090158

Shinjyo N, Waddell G, Green J. Valerian root in treating sleep problems and associated disorders—A systematic review and meta-analysis. Journal of Evidence-Based Integrative Medicine. 2020 Oct; 25: 2515690X20967323. doi: 10.1177/2515690X20967323. DOI: https://doi.org/10.1177/2515690X20967323

Lai Z, Shan W, Li J, Min J, Zeng X, Zuo Z. Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice. Molecular Psychiatry. 2021 Dec; 26(12): 7167-87. doi: 10.1038/s41380-021-01291-y. DOI: https://doi.org/10.1038/s41380-021-01291-y

Abdellah SA, Berlin A, Blondeau C, Guinobert I, Guilbot A, Beck M, et al. A combination of Eschscholtzia californica Cham. and Valeriana officinalis L. extracts for adjustment insomnia: a prospective observational study. Journal of Traditional and Complementary Medicine. 2020 Mar; 10(2): 116-23. doi: 10.1016/j.jtcme.2019.02.003. DOI: https://doi.org/10.1016/j.jtcme.2019.02.003

Kasra Dehkordi A, Ebadi A, Sahraei H, Einollahi B. Effects of aromatherapy with lavender on sleep quality of hemodialysis patients (A Clinical Trial). Nursing And Midwifery Journal. 2016 Feb; 13(11): 995-1003.

Bent S, Padula A, Moore D, Patterson M, Mehling W. Valerian for sleep: a systematic review and meta-analysis. The American Journal of Medicine. 2006 Dec; 119(12): 1005-12. doi: 10.1016/j.amjmed.2006.02.026. DOI: https://doi.org/10.1016/j.amjmed.2006.02.026

Chauhan ES, and Aishwarya J. Nutraceutical analysis of Marticariarecutita (Chamomile) dried leaves and flower powder and comparison between them. International Journal of Phytomedicine. 2018; 10(2): 111-4. doi: 10.5138/09750185.2249. DOI: https://doi.org/10.5138/09750185.2249

Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complementary and Alternative Medicine. 2011 Dec; 11(1): 1-8. doi: 10.1186/1472-6882-11-78. DOI: https://doi.org/10.1186/1472-6882-11-78

Ring M, Marchlewski A, Kaplan J. Dietary supplements for insomnia. Current Sleep Medicine Reports. 2017 Dec; 3: 306-15. doi: 10.1007/s40675-017-0091-2. DOI: https://doi.org/10.1007/s40675-017-0091-2

Chauhan ES, and Jaya A. Chamomile an ancient aromatic plant-A review. Journal of Ayurveda Medical Sciences. 2017; 2(4): 251-5. doi: 10.5530/jams.2017.2.26. DOI: https://doi.org/10.5530/jams.2017.2.26

Salehi B, Venditti A, Sharifi-Rad M, Kręgiel D, Sharifi-Rad J, Durazzo A, et al. The therapeutic potential of apigenin. International Journal of Molecular Sciences. 2019 Mar; 20(6): 1305. doi: 10.3390/ijms20061305. DOI: https://doi.org/10.3390/ijms20061305

Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019 Dec; 65: 153099. doi: 10.1016/j.phymed.2019.153099. DOI: https://doi.org/10.1016/j.phymed.2019.153099

Lanje CN, Patil SR, Wankhade AM. Medicinal natural drug of Valerian (Valerina Officinalis): an-over review. American Journal of PharmaTech Research. 2020; 10(01): 148-73. doi: 10.46624/ajptr. 2020.v10. i1.013. DOI: https://doi.org/10.46624/ajptr.2020.v10.i1.013

Negi R, Chhugani M, Thokchom S, Hooda A. Lavender: A Beneficial Herb for Postnatal Mothers. International Journal of Nursing & Midwifery Research. 2017; 4: 1. doi: 10.24321/2455.9318.201707. DOI: https://doi.org/10.24321/2455.9318.201707

Sharma L, Chandra M, Puneeta A. Health benefits of lavender (Lavandula angustifolia). International Journal of Physiology, Nutrition and Physical Education. 2020; 4(1): 1274-7.

Zeng Y, Yang J, Du J, Pu X, Yang X, Yang S, et al. Strategies of functional foods promote sleep in human being. Current Signal Transduction Therapy. 2014 Dec; 9(3): 148-55. doi: 10.2174/1574362410666150205165504. DOI: https://doi.org/10.2174/1574362410666150205165504

Doherty R, Madigan S, Warrington G, Ellis J. Sleep and nutrition interactions: implications for athletes. Nutrients. 2019 Apr; 11(4): 822. doi: 10.3390/nu11040822. DOI: https://doi.org/10.3390/nu11040822