Effect of Trachyspermum ammi essential oil, fractions and its derivatives on resistant fungal Strains: Effect of Trachyspermum ammi Essential oil, & fungal Strains

Naila  Iram; Muhammad Asif  Hanif; Haq Nawaz  Bhatti; Muhammad  Shahid

doi:10.54393/pbmj.v4i2.153

Authors

Naila Iram Department of chemistry, Faculty of sciences, University of Agriculture, Faisalabad, Pakistan
Muhammad Asif Hanif Department of chemistry, Faculty of sciences, University of Agriculture, Faisalabad, Pakistan
Haq Nawaz Bhatti Department of chemistry, Faculty of sciences, University of Agriculture, Faisalabad, Pakistan
Muhammad Shahid Department of Biochemistry, Faculty of sciences, University of Agriculture, Faisalabad , Pakistan

DOI:

https://doi.org/10.54393/pbmj.v4i2.153

Abstract

Persistentantimicrobial drugs treatmenthas resulted in antimicrobial resistance in fungi. There is always a gap for newer antifungal agent. As fungi are associated with multiple health risks in humans and many diseases in crops as well.Objective: To find alternate natural antimicrobial agent as compared to the synthetic one. Method:Essential oil of Trachyspermumammi was isolated, fractionated, and subjected to GC-MS analysis. Components from fractions were derivatized to check their antimicrobial potential against fungal resistant strains. Results:Analysis showed γ -terpinene (39%), α-phellandrene (1.3%), α-pinene (0.5%), Sabinene (0.15%), β-pinene (4.40%), β-myrcene (1.14%), O-cymene (15.78%), p-cymefne (38.78%), and other components were less than 1%. Fractional components were derivatised and their antifungal action was studied. Conclusion: Ajwain oil components found to be good against resistant fungal strains. While some derivatives showed more and some less antimicrobial action.

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