Risk Factors Associated with Cardiovascular Disorders
Risk Factors Associated with Cardiovascular Disorders
DOI:
https://doi.org/10.54393/pbmj.v7i02.1034Keywords:
Cardiovascular Disorders, Risk Factors, Obesity, Diabetes, SmokingAbstract
Cardiovascular diseases (CVDs) constitute the primary cause of mortality worldwide. 32% of all fatalities globally in 2019 were attributed to CVDs, with an estimated 17.9 million deaths. Heart attacks and strokes were the significant cause of 85% of these fatalities. More than 75% of fatalities from CVD occur in low- and middle-income nations. In 2019, non-communicable illnesses accounted for 17 million premature fatalities (deaths under 70 years of age) of which 38% were attributable to CVDs. An increased risk of acquiring high blood pressure (hypertension), high cholesterol, and Type 2 diabetes can also be attributed to a family history of these disorders. These conditions can also raise an individual's risk of cardiovascular disease. By addressing behavioral risk factors such as tobacco use, bad food and obesity, physical inactivity, and problematic alcohol consumption, most cardiovascular illnesses may be averted. Early detection of cardiovascular illness is crucial for the commencement of medication and counseling-based therapy.
References
Callow AD. Cardiovascular disease 2005—the global picture. Vascular Pharmacology. 2006 Nov ; 45(5): 302-7. DOI: https://doi.org/10.1016/j.vph.2006.08.010
McPherson R and Tybjaerg-Hansen A. Genetics of coronary artery disease. Circulation Research. 2016 Feb ; 118(4): 564-78. DOI: https://doi.org/10.1161/CIRCRESAHA.115.306566
Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nature Reviews Nephrology. 2020 Apr; 16(4): 223-37. DOI: https://doi.org/10.1038/s41581-019-0244-2
Rossignol P, Hernandez AF, Solomon SD, Zannad F. Heart failure drug treatment. The Lancet. 2019 Mar;393(10175): 1034-44. DOI: https://doi.org/10.1016/S0140-6736(18)31808-7
Gopinathannair R, Etheridge SP, Marchlinski FE, Spinale FG, Lakkireddy D, Olshansky B. Arrhythmia-induced cardiomyopathies: mechanisms, recognition, and management. Journal of the American College of Cardiology. 2015 Oct; 66(15): 1714-28. DOI: https://doi.org/10.1016/j.jacc.2015.08.038
Saef J and Ghobrial J. Valvular heart disease in congenital heart disease: a narrative review. Cardiovascular Diagnosis and Therapy. 2021 Jun; 11(3): 818. DOI: https://doi.org/10.21037/cdt-19-693-b
World Health Organization. Cardiovascular diseases (CVDs) fact sheet. [Last cited: 22 Feb 2024]. Available at: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).
Hopgood DA, Haile ZT, Conley S, Chertok IR. Association between acculturation and sociodemographic factors and cardiovascular disease among immigrants to the United States. Public Health Nursing. 2021 Jan; 38(1): 47-55. DOI: https://doi.org/10.1111/phn.12825
Zhang YB, Pan XF, Chen J, Cao A, Xia L, Zhang Y, et al. Combined lifestyle factors, all-cause mortality and cardiovascular disease: a systematic review and meta-analysis of prospective cohort studies. Journal of Epidemiology and Community Health. 2021 Jan 1; 75(1): 92-9.
American Heart Association. Understanding your risk for cardiovascular disease. [Last cited: 22 Feb 2024]. Available at: https://www.heart.org/en/health-topics/heart-attack/understand-your-risks-to-prevent-a-heart-attack.
Teo K, Chow CK, Vaz M, Rangarajan S, Yusuf S. PURE Investigators-Writing Group. The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries. American Heart Journal. 2009 Jul; 158(1): 1-7. doi: 10.1016/j.ahj.2009.04.019. DOI: https://doi.org/10.1016/j.ahj.2009.04.019
Samb B, Desai N, Nishtar S, Mendis S, Bekedam H, Wright A et al. Chronic diseases: chronic diseases and development 4 prevention and management of chronic disease: a litmus test for health-systems strengthening in low-income and middle-income countries. Lancet. 2010 Nov; 376(9754): 1785-97. doi: 10.1016/S0140-6736(10)61353-0. DOI: https://doi.org/10.1016/S0140-6736(10)61353-0
Psaltopoulou T, Hatzis G, Papageorgiou N, Androulakis E, Briasoulis A, Tousoulis D. Socioeconomic status and risk factors for cardiovascular disease: impact of dietary mediators. Hellenic Journal of Cardiology. 2017 Jan; 58(1): 32-42. doi: 10.1016/j.hjc.2017.01.022. DOI: https://doi.org/10.1016/j.hjc.2017.01.022
Alam AY, Iqbal A, Mohamud KB, Laporte RE, Ahmed A, Nishtar S. Investigating socio-economic-demographic determinants of tobacco use in Rawalpindi, Pakistan. BMC Public Health. 2008 Dec; 8:1-9. doi: 10.1186/1471-2458-8-50. DOI: https://doi.org/10.1186/1471-2458-8-50
Abbas S, Kitchlew AR, Abbas S. Disease burden of ischemic heart disease in Pakistan and its risk factors. Ann Pakistan Institute of Medical Sciences. 2009; 5(3): 145-50.
Jafar TH, Chaturvedi N, Pappas G. Prevalence of overweight and obesity and their association with hypertension and diabetes mellitus in an Indo-Asian population. Canadian Medical Association Journal. 2006 Oct; 175(9): 1071-7. doi: 10.1503/cmaj.060464 . DOI: https://doi.org/10.1503/cmaj.060464
World Health Organization. Burden: mortality, morbidity and risk factors. In: Alwan A, editor. Global Status Report on Noncommunicable Diseases 2010. Geneva: World Health Organization; 2011. [Last cited: 22 Feb 2024]. Available at: https://www3.paho.org/hq/dmdocuments/2012/WHO-Global-Status-Report-NCDs-2010-Eng.pdf.
Rifat-uz-Zaman ZI and Ali U. Dietary intakes of urban adolescents of sialkot, Pakistan do not meet the standards of adequacy. Pakistan Journal of Nutrition. 2013; 12: 460-7. doi: 10.3923/pjn.2013.460.467. DOI: https://doi.org/10.3923/pjn.2013.460.467
Bastien M, Poirier P, Lemieux I, Després JP. Overview of epidemiology and contribution of obesity to cardiovascular disease. Progress in Cardiovascular Diseases. 2014 Jan; 56(4): 369-81. doi: 10.1016/j.pcad.2013.10.016. DOI: https://doi.org/10.1016/j.pcad.2013.10.016
Jafar TH, Haaland BA, Rahman A, Razzak JA, Bilger M, Naghavi M et al. Non-communicable diseases and injuries in Pakistan: strategic priorities. The Lancet. 2013 Jun; 381(9885): 2281-90. doi: 10.1016/s0140-6736(13)60646-7. DOI: https://doi.org/10.1016/S0140-6736(13)60646-7
Yoon PW, Scheuner MT, Peterson-Oehlke KL, Gwinn M, Faucett A, Khoury MJ. Can family history be used as a tool for public health and preventive medicine?. Genetics in Medicine. 2002 Jul; 4(4): 304-10. doi: 10.1097/00125817-200207000-00009. DOI: https://doi.org/10.1097/00125817-200207000-00009
American Heart Association. Heart disease and stroke statistics: 2003 Update. Dallas, Texas: American Heart Association. 2002. [Last cited: 20 Feb 2024]. Available at: http://www.americanheart.org/downloadable/heart/1040391091015HDS_Stats_03.pdf. Accessed February 10, 2003.
Goldstein LB, Adams R, Becker K, Furberg CD, Gorelick PB, Hademenos G et al. Primary prevention of ischemic stroke. Circulation. 2001 Jan; 103(1): 163-82. doi: 10.1161/01.CIR.103.1.163. DOI: https://doi.org/10.1161/01.CIR.103.1.163
Hahn RA, Heath GW, Chang MH. Cardiovascular disease risk factors and preventive practices among adults—United States, 1994: a behavioral risk factor atlas. Morbidity And Mortality Weekly Report: CDC Surveillance Summaries. 1998 Dec: 35-69.
Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, Fortmann SP et al. AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. Circulation. 2002 Jul; 106(3): 388-91. doi: 10.1161/01.CIR.0000020190.45892.75. DOI: https://doi.org/10.1161/01.CIR.0000020190.45892.75
Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The lancet. 2012 Dec; 380(9859): 2224-60.
Ambrose JA and Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. Journal of the American College of Cardiology. 2004 May; 43(10): 1731-7. doi|: 10.1016/j.jacc.2003.12.047. DOI: https://doi.org/10.1016/j.jacc.2003.12.047
World Health Organization. Report on the Global Tobacco Control Report: Country Profile, Pakistan 2015: 1-7. [Last Cited: 22 Feb 2024]. Available at: http://who.int/tobacco/ economics/country profile/pak.pdf.
Nishtar S. Vision 2030 of the Planning Commission of Pakistan - strategic health imperatives. Heart File. 2006; 5:1.
Turin TC, Shahana N, Wangchuk LZ, Specogna AV, Al Mamun M, Khan Mab et al. Burden of cardio-and cerebro-vascular diseases and the conventional risk factors in South Asian population. Global Heart. 2013 Jun; 8(2): 121-30. doi: 10.1016/j.gheart.2012.01.001. DOI: https://doi.org/10.1016/j.gheart.2012.01.001
Gilani SI, Leon DA. Prevalence and sociodemographic determinants of tobacco use among adults in Pakistan: findings of a nationwide survey conducted in 2012. Population Health Metrics. 2013 Dec; 11(1):1-1. doi: 10.1186/1478-7954-11-16. DOI: https://doi.org/10.1186/1478-7954-11-16
Safdar NF, Bertone-Johnson ER, Cordeiro L, Jafar TH, Cohen NL. Dietary patterns and their association with hypertension among Pakistani urban adults. Asia Pacific Journal of Clinical Nutrition. 2015 Dec; 24(4): 710-9.
Jawaid A, Zafar AM, Rehman TU, Nazir MR, Ghafoor ZA, Afzal O, Khan JA. Knowledge, attitudes and practice of university students regarding waterpipe smoking in Pakistan. The International Journal of Tuberculosis And Lung Disease. 2008 Sep; 12(9): 1077-84.
Jafar TH, Qadri Z, Chaturvedi N. Coronary artery disease epidemic in Pakistan: more electrocardiographic evidence of ischaemia in women than in men. Heart. 2008 Apr; 94(4): 408-13. doi: 10.1136/hrt.2007.120774. DOI: https://doi.org/10.1136/hrt.2007.120774
Irazola VE, Gutierrez L, Bloomfield GS, Carrillo-Larco RM, Dorairaj P, Gaziano T et al. Hypertension prevalence, awareness, treatment, and control in selected communities of nine low-and middle income countries: results from the NHLBI/UHG Network of Centers of Excellence for Chronic Diseases. Global Heart. 2016 Mar; 11(1): 47. doi: 10.1016/j.gheart.2015.12.008. DOI: https://doi.org/10.1016/j.gheart.2015.12.008
Aslam N, Shoaib MH, Bushra R, Farooqi FA, Zafar F, Ali H, Saleem S. Out of pocket (OOP) cost of treating hypertension in Karachi, Pakistan. Pakistan journal of pharmaceutical sciences. 2018 May; 31.
Meghani ST, Sehar S, Punjani NS. Comparison and analysis of health care delivery system: Pakistan versus China. International Journal of Endorsing Health Science Research. 2014 Jun; 2(1): 46-9. doi: 10.29052/IJEHSR.v2.i1.2014.46-50. DOI: https://doi.org/10.29052/IJEHSR.v2.i1.2014.46-50
Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, Moore SC, Tobias GS, Anton-Culver H, Freeman LB, Beeson WL. Body-mass index and mortality among 1.46 million white adults. New England Journal of Medicine. 2010 Dec; 363(23): 2211-9. doi: 10.1056/NEJMoa1000367. DOI: https://doi.org/10.1056/NEJMoa1000367
Collaborators GBDO, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K et al. Health effects of overweight and obesity in 195 countries over 25 years. The New England Journal of Medicine. 2017; 377:13–27. doi: 10.1056/NEJMoa1614362. DOI: https://doi.org/10.1056/NEJMoa1614362
Saab J and Salvatore SP. Evaluating the cause of death in obese individuals: a ten-year medical autopsy study. Journal of Obesity. 2015 Jan; 2015. doi: 10.1155/2015/695374. DOI: https://doi.org/10.1155/2015/695374
Bays HE, McCarthy W, Christensen S, Tondt J, Karjoo S, Davisson L. Obesity algorithm eBook, presented by the Obesity Medicine Association; 2021.
Khera A, Baum SJ, Gluckman TJ, Gulati M, Martin SS, Michos ED et al. Continuity of care and outpatient management for patients with and at high risk for cardiovascular disease during the COVID-19 pandemic: A scientific statement from the American Society for Preventive Cardiology. American journal of preventive cardiology. 2020 Mar; 1: 100009. doi: 10.1016/j.ajpc.2020.100009. DOI: https://doi.org/10.1016/j.ajpc.2020.100009
George CE, Ramadas D, Norman G, Mukherjee D, Rao T. Barriers to cardiovascular disease risk reduction: Does physicians’ perspective matter?. Indian Heart Journal. 2016 May; 68(3): 278-85. doi: 10.1016/j.ihj.2015.08.014. DOI: https://doi.org/10.1016/j.ihj.2015.08.014
Fürthauer J, Flamm M, Sönnichsen A. Patient and physician related factors of adherence to evidence based guidelines in diabetes mellitus type 2, cardiovascular disease and prevention: a cross sectional study. BMC Family Practice. 2013 Dec; 14(1): 1-8. doi: 10.1186/1471-2296-14-47. DOI: https://doi.org/10.1186/1471-2296-14-47
Narula J and Prabhakaran D. Tobacco, and CVD. Global Heart 2012; 7: 195-6. doi: 10.1016/j.gheart.2012.07.001. DOI: https://doi.org/10.1016/j.gheart.2012.07.001
Pakistan Medical Research Council. National Health Survey of Pakistan 1990 -1994. 1998 [Last Cited: 22 Feb 2024]. Available at: http://www.statpak.gov.pk/depts/pco/.
Danaei G, Lawes CM, Vander Hoorn S, Murray CJ, Ezzati M. Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. The Lancet. 2006 Nov; 368(9548): 1651-9. doi: 10.1016/S0140-6736(06)69700-6. DOI: https://doi.org/10.1016/S0140-6736(06)69700-6
Emerging Risk Factors Collaboration. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. The lancet. 2010 Jun; 375(9733): 2215-22. doi: 10.1016/S0140-6736(10)60484-9. DOI: https://doi.org/10.1016/S0140-6736(10)60484-9
Chomistek AK, Manson JE, Stefanick ML, Lu B, Sands-Lincoln M, Going SB et al. Relationship of sedentary behavior and physical activity to incident cardiovascular disease: results from the Women's Health Initiative. Journal of the American College of Cardiology. 2013 Jun; 61(23): 2346-54. doi: 10.1016/j.jacc.2013.03.031. DOI: https://doi.org/10.1016/j.jacc.2013.03.031
Giménez M, López JJ, Castell C, Conget I. Hypoglycaemia and cardiovascular disease in Type 1 Diabetes. Results from the Catalan National Public Health registry on insulin pump therapy. Diabetes Research and Clinical Practice. 2012 May; 96(2): e23-5. doi: 10.1016/j.diabres.2012.01.014. DOI: https://doi.org/10.1016/j.diabres.2012.01.014
Eeg-Olofsson K, Cederholm J, Nilsson PM, Zethelius B, Svensson AM, Gudbjörnsdóttir S et al. Glycemic control and cardiovascular disease in 7,454 patients with type 1 diabetes: an observational study from the Swedish National Diabetes Register (NDR). Diabetes Care. 2010 Jul; 33(7): 1640-6. doi: 10.2337/dc10-0398. DOI: https://doi.org/10.2337/dc10-0398
Bragg F, Li L, Smith M, Guo Y, Chen Y, Millwood I, Bian Z, Walters R, Chen J, Yang L, Collins R. Associations of blood glucose and prevalent diabetes with risk of cardiovascular disease in 500 000 adult Chinese: the China Kadoorie Biobank. Diabetic Medicine. 2014 May; 31(5): 540-51. doi: 10.1111/dme.12392. DOI: https://doi.org/10.1111/dme.12392
Abegunde DO, Mathers CD, Adam T, Ortegon M, Strong K. The burden and costs of chronic diseases in low-income and middle-income countries. The Lancet. 2007 Dec; 370(9603): 1929-38. doi: 10.1016/S0140-6736(07)61696-1. DOI: https://doi.org/10.1016/S0140-6736(07)61696-1
Klatsky AL. Alcohol and cardiovascular diseases. Expert Review of Cardiovascular Therapy. 2009 May; 7(5): 499-506. doi: 10.1586/erc.09.22. DOI: https://doi.org/10.1586/erc.09.22
Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Comprehensive Physiology. 2012 Apr; 2(2): 1143. doi: 10.1002/cphy.c110025. DOI: https://doi.org/10.1002/cphy.c110025
World Health Organization. World Health Statistics. 2008. [Last cited: 22 Feb 2024]. Available at: https://www.who.int/docs/default-source/gho-documents/world-health-statistic-reports/en-whs08-full.pdf.
Félix-Redondo FJ, Grau M, Fernández-Bergés D. Cholesterol and cardiovascular disease in the elderly. Facts and gaps. Aging and disease. 2013 Jun; 4(3): 154.
Dzau VJ, Antman EM, Black HR, Hayes DL, Manson JE, Plutzky J et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006 Dec; 114(25): 2850-70. doi: 10.1161/CIRCULATIONAHA.106.655688. DOI: https://doi.org/10.1161/CIRCULATIONAHA.106.655688
Ross R. Atherosclerosis—an inflammatory disease. New England Journal of Medicine. 1999 Jan; 340(2): 115-26. doi: 10.1056/NEJM199901143400207. DOI: https://doi.org/10.1056/NEJM199901143400207
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