Frequency Of Ovarian Artery Doppler Indices in Patients of Polycystic Ovarian Syndrome

Ovarian Artery Doppler Indices in Patients of Polycystic Ovarian Syndrome

Authors

  • Zubair Janan Orakzai Diagnostic Radiology, Bkmc / Mmc, Mardan
  • Tabassum Begum Diagnostic Radiology, Bkmc / Mmc, Mardan
  • Bakht Rokhan Saidu Medical College / Saidu Teaching Hospital Saidu Sharif Swat
  • Fahmida Sattar Gynae/Obs, Seikh Khalifa Bin Zayed Hospital Quetta
  • Fauzia Rashid HBS General Hospital Islamabad
  • Ayesha Kamran Sargodha Medical College Dhq Hospital Sargodha

DOI:

https://doi.org/10.54393/pbmj.v5i6.549

Keywords:

Doppler Ultrasound, Polycystic Ovarian Syndrome, Deranged ovarian artery, Doppler indices.

Abstract

Polycystic ovarian syndrome (PCOS) is a common endocrine disorder. It is characterized by changes in Doppler indices of ovarian arteries. These changes are more prominent than the morphological changes of ovary and uterus. Objective: The aim of the analysis was to calculate the percentage of deranged ovarian artery in patients with polycystic ovarian syndrome ovarian patients. Methods: This observational study was conducted on total 225 women of reproductive age ranging between 18-40 years presented with the PCOS at the hospital. The gold standard for diagnosis of deranged ovarian artery in PCOS is transvaginal ultrasound. The Doppler ultrasound helps to calculate the resistive and pulsatility indices of ovarian artery. The pulsatility Index and Resistive Index was calculated and percentage frequency was estimated from the calculated results. Ovarian blood flow is deranged if its indices are above or below the normal range. The resistive index (RI) measured by Doppler imaging was between 0.80 to 0.95 and pulsatility index (PI) range was between 2.01 to 4.30. The data were arranged according to BMI of patients. The age and duration of PCOS were also considered for data stratification. Results: The study showed that about 191 (85%) patients out of 225 with PCOS have deranged ovarian artery Doppler. The range of pulsatility index was between 2.01 to 4.30 while the range of resistive index was between 0.80 to 0.95. The mean duration of PCOS and means age of patient was calculated. It was found that the deranged ovarian blood flow was more common in the women of age 27-5.9 years. 18.4-7.1 months was the mean duration of PCOS. The mean BMI of the patient was 27.2-4.9kg/m2.Conclusion: A significant number of women suffering from PCOS have deranged ovarian artery Doppler indices. This study evaluated the putative role of Doppler indices in diagnosis of suspicious PCOS patients.

References

Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clinical epidemiology. 2014; 6:1.doi.org/10.2147/CLEP.S37559

Solomon CG. The epidemiology of polycystic ovary syndrome: prevalence and associated disease risks. Endocrinology and metabolism clinics of North America. 1999 Jun; 28(2):247-63. doi.org/10.1016/S0889-8529(05)70069-4

Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nature reviews endocrinology. 2011 Apr; 7(4):219-31. doi.org/10.1038/nrendo.2010.217

Dhingra D, Prateek S, Sinha R, Agarwal Y. Doppler flow velocities of uterine and ovarian arteries & hormonal patterns in patients with Polycystic Ovary Syndrome (PCOS). International Journal of Healthcare and Biomedical Research. 2017 Jul; 5(04):48-57.

Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E. American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society disease state clinical review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome-part 2. Endocrine Practice. 2015 Dec; 21(12):1415-26. doi.org/10.4158/EP15748.DSCPT2

Hart R, Hickey M, Franks S. Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome. Best Practice & Research Clinical Obstetrics & Gynaecology. 2004 Oct; 18(5):671-83. doi.org/10.1016/j.bpobgyn.2004.05.001

Bano A. Diagnosis of Polycystic Ovarian Syndrome on Doppler Based Resistive Index and Pulsatility Index. Journal of Rawalpindi Medical College. 2016 Dec; 20(4):305-8.

Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, et al. Diagnosis and treatment of polycystic ovary syndrome: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism. 2013 Dec; 98(12):4565-92. doi.org/10.1210/jc.2013-2350

Rotterdam ESHRE/ASRM‐Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long‐term health risks related to polycystic ovary syndrome (PCOS). Human reproduction. 2004 Jan; 19(1):41-7. doi.org/10.1093/humrep/deh098

Dokras A. Heart health in polycystic ovary syndrome: time to act on the data. Fertility and Sterility. 2022 May 1;117(5):885-6.doi.org/10.1016/j.fertnstert.2022.03.014

Giri A, Joshi A, Shrestha S, Chaudhary A. Metabolic Syndrome among Patients with Polycystic Ovarian Syndrome Presenting to a Tertiary Care Hospital: A Descriptive Cross-Sectional Study. Journal of the Nepal Medical Association. 2022 Feb; 60(246). doi.org/10.31729/jnma.7221

Kovacs GT, Fauser B, Legro RS, editors. Polycystic ovary syndrome. Cambridge University Press; 2022 May 31. doi.org/10.1017/9781108989831

Vrtacnik-Bokal E, Meden-Vrtovec H. Utero-ovarian arterial blood flow and hormonal profile in patients with polycystic ovary syndrome. Human reproduction (Oxford, England). 1998 Apr; 13(4):815-21. doi.org/10.1093/humrep/13.4.815

Artini PG, Di Berardino OM, Simi G, Papini F, Ruggiero M, Monteleone P, et al. Best methods for identification and treatment of PCOS. Minerva ginecologica. 2010 Feb; 62(1):33.

Akram M, Roohi N. Endocrine correlates of polycystic ovary syndrome in Pakistani women. Journal of the College of Physicians and Surgeons Pakistan. 2015 Jan 1;25(1):22-6.

Bano A. Diagnosis of Polycystic Ovarian Syndrome on Doppler Based Resistive Index and Pulsatility Index. Journal of Rawalpindi Medical College. 2016 Dec; 20(4):305-8.

Wahab S, Karim R. Role of Metformin in Polycystic Ovarian Syndrome. JPMI: Journal of Postgraduate Medical Institute. 2013 Apr; 27(2).

Usmani A, Rehman R, Akhtar Z. Association of Body Mass Index and Dietary Habits with Ovarian and Uterine Morphology with Subfertile Polycystic Ovarian Syndrome. JPMI: Journal of Postgraduate Medical Institute. 2014 Apr; 28(2).

Maciołek-Blewniewska G, Kozarzewski M, Szpakowski M, Pertyński T, Nowak M. The evaluation of blood flow in uterine arteries in girls with polycystic ovary syndrome by transvaginal color Doppler ultrasonography. Ginekologia polska. 1999 May; 70(5):412-7.

Aleem FA, Predanic M. Transvaginal color Doppler determination of the ovarian and uterine blood flow characteristics in polycystic ovary disease. Fertility and sterility. 1996 Mar; 65(3):510-6. doi.org/10.1016/S0015-0282(16)58145-X

Qazi II, Qazi AT, Ijaz F, Jawed S, Aftab RK, Qazi SR. Relationship of obesity with insulin resistance in polycystic ovarian syndrome. Pakistan Journal of Physiology. 2018 Aug; 14(3):46-9.

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Published

2022-06-30
CITATION
DOI: 10.54393/pbmj.v5i6.549
Published: 2022-06-30

How to Cite

Janan Orakzai, Z. ., Begum, T., Rokhan, B. ., Sattar, F. ., Rashid , F. ., & Kamran, A. . (2022). Frequency Of Ovarian Artery Doppler Indices in Patients of Polycystic Ovarian Syndrome: Ovarian Artery Doppler Indices in Patients of Polycystic Ovarian Syndrome. Pakistan BioMedical Journal, 5(6), 150–154. https://doi.org/10.54393/pbmj.v5i6.549

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