Leukocytosis and thrombocytopenia in pre-partum, post-partum cases and non-pregnant women: Leukocytosis and thrombocytopenia in pre-partum, post-partum cases and non-pregnant women

Afia  Akhter; Fatima  Saleem; Mian Muhammad Jehanzeb; Bushra  Mubarak; Kainat  Waheed; Iqra  Munir; Marya  Saadullah; Masooma  Anwar

doi:10.54393/pbmj.v5i6.551

Authors

Afia Akhter University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Fatima Saleem University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Mian Muhammad Jehanzeb Bahria Town International Hospital
Bushra Mubarak University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Kainat Waheed University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Iqra Munir University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Marya Saadullah University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore
Masooma Anwar University Institute of Medical Laboratory Sciences, The University of Lahore, Lahore

DOI:

https://doi.org/10.54393/pbmj.v5i6.551

Keywords:

Leukocytosis, Thrombocytopenia, Anemia, Pre-partum, Post-partum

Abstract

Thrombocytopenia is a serious condition that may cause fatal outcomes for both mother and infant, whereas leukocytosis is an essential mediator of the inflammatory process and a marker for infection during pregnancy. Objective: The aim of the study was to compare the frequency of thrombocytopenia and leukocytosis among pre-partum, post-partum cases and non-pregnant healthy controls. Methods: Total 600 samples were collected and categorized into three groups, pre-partum, post-partum and non-pregnant 200 in each. From selected groups 3-5 ml blood was collected in EDTA tube and Sodium Citrate vial. Platelets, WBCs, RBCs and Hemoglobin levels were analyzed on Sysmex KX-21. PT and APTT of all samples was performed manually. Results: Leukocytosis was detected in 60% pre-partum and 64% post-partum, there was not statistically significant difference (p=0.596). In pregnant and non-pregnant, there was significant difference statistically (p<0.05). Thrombocytopenia was detected in 11% pre-partum, 13% post-partum cases and there was no statistical difference (p>0.05). There was statistical difference in frequency of thrombocytopenia between pregnant and non-pregnant women (p=0.03). There was no statistically significant difference in PT and APTT between pre-partum and post-partum (p>0.05). APTT were significantly different between pregnant and non-pregnant cases (p<0.05). Conclusion: The study concluded that leukocytosis and thrombocytopenia was found in higher frequency among pregnant women than non-pregnant women but there was no significant difference in frequency of leukocytosis and thrombocytopenia between pre-partum and post-partum women

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