Exploring The Effect of Mutigrain Flour on Glycemic Index of Diabetic Rats Model

Effect of Multigrain Flour on Glycemic Index in rats

Authors

  • Sehrish Rafique University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore.
  • Shaista Jabeen University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore
  • Tabussam Tufail University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore
  • Huma Bader Ul Ain University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore
  • Rizwan Shoukat University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore
  • Zarina Yasmin Post-Harvest Research Centre, Ayub Agricultural Research Institute, Faisalabad, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i7.620

Keywords:

Multigrain, Diabetes, Glycemic Index, Cereals, Glucose

Abstract

The glycemic index is a measure that assesses the quantity of carbohydrates in meals on a range of zero to 100, reflecting how rapidly an item raises blood sugar. Multigrain flour stayed active for eating, and it had greater storage stability. Objective: To evaluate the effect of multigrain flour on glycemic index and insulin levels of diabetic rats. Methods: The Current study was designed to evaluate the effect of multigrain flour on diabetes. Sample size was 60 male rats (3 groups were made) 20 in each group and Convenient sampling was used. Proximate chemical analysis of the multigrain flour was also done. SPSS version 24.0 was used to tabulate and analyse the data. Results: Highest feed intake at week 1 was (24.10 ± 0.48 g/rat) and highest feed intake at week 4 was (25.80 ± 0.95 g/rat). Highest water intake at week 1 was (21.03 ± 0.51 mL/rat) and highest water intake at week 4 was (25.52 ± 0.54mL/rat). Highest blood glucose level at 0-day was (177.27 ± 2.40 mg/dL) and highest blood glucose level at 30th day was (149.57 ± 4.51mg/dL). Highest glycemic index value at week 1 (0-minute) was (136±2.04), highest glycemic index value at week 1 (30-minute) was (165 ± 2.47), highest glycemic index value at week 1 (60-minute) was (165 ± 2.47). Conclusions: This approach is also beneficial in the management of a variety of disorders. The addition of micronutrients to multi grain flour can boost the nutritional content of goods while also extending their shelf life.

References

Laskowski W, Górska-Warsewicz H, Rejman K, Czeczotko M, Zwolińska J. How Important are Cereals and Cereal Products in the Average Polish Diet?. Nutrients. 2019 Mar; 11(3):679. doi: 10.3390/nu11030679

Muhammad HS, Muhammad FS, Muhammad S, Niaz AQ, Safia M. The importance of cereals (Poaceae: Gramineae) nutrition in human health: A review. Journal of cereals and oilseeds. 2013 Jun; 4(3):32-5. doi: 10.5897/JCO12.023

Frølich W and Aman P. Whole grain for whom and why?. Food and Nutrition Research. 2010 Mar; 54. doi: 10.3402/fnr.v54i0.5056

Harreiter J and Roden M. Diabetes mellitus-Definition, classification, diagnosis, screening and prevention (Update 2019). Wiener Klinische Wochenschrift. 2019 May; 131(Suppl 1):6-15. doi: 10.1007/s00508-019-1450-4

Li W, Huang E, Gao S. Type 1 Diabetes Mellitus and Cognitive Impairments: A Systematic Review. Journal of Alzheimers Disease. 2017; 57(1):29-36. doi: 10.3233/JAD-161250

Mounika D and Sireesha G. Development of Multigrain Flour. In International Conference On Computational And Bio Engineering. Springer, Cham. 2019 Dec: 161-8. doi: 10.1007/978-3-030-46943-6_19

Kishorgoliya N, Mehra M, Goswami P. Nutritional quality of the developed multigrain flour and cookies. Journal of Pharmacognosy and Phytochemistry. 2018; 7:2886-8.

Foster-Powell K and Miller JB. International tables of glycemic index. The American Journal of Clinical Nutrition. 1995 Oct; 62(4):871S-890S. doi: 10.1093/ajcn/62.4.871S.

Jenkins DJ, Kendall CW, Augustin LS, Franceschi S, Hamidi M, Marchie A, et al. Glycemic index: overview of implications in health and disease. The American Journal of Clinical Nutrition. 2002 Jul; 76(1):266S-73S. doi: 10.1093/ajcn/76/1.266S

Nagaraju R, Sobhana PP, Thappatla D, Epparapalli S, Kandlakunta B, Korrapati D. Glycemic Index and Sensory Evaluation of Whole Grain Based Multigrain Indian Breads (Rotis). Preventive Nutrition and Food Science. 2020 Jun; 25(2):194-202. doi: 10.3746/pnf.2020.25.2.194

Xiong Y, Zhang P, Warner RD, Fang Z. Sorghum Grain: From Genotype, Nutrition, and Phenolic Profile to Its Health Benefits and Food Applications. Comprehensive Reviews in Food Science and Food Safety. 2019 Nov; 18(6):2025-2046. doi: 10.1111/1541-4337.12506.

Zhang X, McGeoch SC, Megson IL, MacRury SM, Johnstone AM, Abraham P, et al. Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes. Molecular Nutrition and Food Research. 2014 Jun; 58(6):1322-32. doi: 10.1002/mnfr.201300820

Radhika G, Sumathi C, Ganesan A, Sudha V, Jeya Kumar Henry C, Mohan V. Glycaemic index of Indian flatbreads (rotis) prepared using whole wheat flour and 'atta mix'-added whole wheat flour. British Journal of Nutrition. 2010 Jun; 103(11):1642-7. doi: 10.1017/S0007114509993680

Venn BJ and Green TJ. Glycemic index and glycemic load: measurement issues and their effect on diet-disease relationships. European Journal of Clinical Nutrition. 2007 Dec; 61 Suppl 1:S122-31. doi: 10.1038/sj.ejcn.1602942

Qi L, van Dam RM, Liu S, Franz M, Mantzoros C, Hu FB. Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women. Diabetes Care. 2006 Feb; 29(2):207-11. doi: 10.2337/diacare.29.02.06.dc05-1903

Tufail T, Saeed F, Ain HB, Niaz B, Afzaal M, Din A, et al. Cashew nut allergy; immune health challenge. Trends in Food Science & Technology. 2019 Apr; 86:209-16. doi: 10.1016/j.tifs.2019.02.014

Meynier A, Goux A, Atkinson F, Brack O, Vinoy S. Postprandial glycaemic response: how is it influenced by characteristics of cereal products? British Journal of Nutrition. 2015 Jun; 113(12):1931-9. doi: 10.1017/S0007114515001270.

Brennan CS. Dietary fibre, glycaemic response, and diabetes. Molecular Nutrition and Food Research. 2005 Jun; 49(6):560-70. doi: 10.1002/mnfr.200500025

Indrani D, Soumya C, Rajiv J, Venkateswara Rao G. Multigrain bread–its dough rheology, microstructure, quality and nutritional characteristics. Journal of texture studies. 2010 Jun; 41(3):302-19. doi: 10.1111/j.1745-4603.2010.00230.x

Liu Y, Ye F, Zhang S, Li S, Chen J. Characteristics of myoelectrical activities along the small intestine and their responses to test meals of different glycemic index in rats. American Journal of Physiology, Regulatory Integrative and Comparative Physiology. 2020 May; 318(5):R997-R1003. doi: 10.1152/ajpregu.00282.2019

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Published

2022-07-31
CITATION
DOI: 10.54393/pbmj.v5i7.620
Published: 2022-07-31

How to Cite

Rafique, S. ., Jabeen, S. ., Tufail, T. ., Bader Ul Ain, H., Shoukat, R. ., & Yasmin, Z. . (2022). Exploring The Effect of Mutigrain Flour on Glycemic Index of Diabetic Rats Model: Effect of Multigrain Flour on Glycemic Index in rats . Pakistan BioMedical Journal, 5(7), 265–268. https://doi.org/10.54393/pbmj.v5i7.620

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