Utilization of Probiotics in Treatment of Gastrointestinal Infections among Children

Probiotics in Treatment of Gastrointestinal Infections among Children

Authors

  • Azka Fatima University Institute of Public Health, Faculty of Allied Health Sciences, The University of Lahore, Pakistan
  • Salsbeel Khan University Institute of Public Health, Faculty of Allied Health Sciences, The University of Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i9.786

Keywords:

Probiotics, Gastrointestinal Infections, Treatment, Children

Abstract

Probiotics have been extensively studied and examined globally. Probiotics are extremely important for human health and encourage the growth of good bacteria in the human body. Probiotics exert its beneficial effect in the human body through a number of mechanisms, including the production of antibacterial chemicals, the eradication of pathogenic bacteria, and the prevention of the synthesis of toxic substances. Probiotics are now available in the market as functional foods and dietary supplements. The probiotics market is expected to increase from $35.6 billion in 2015 to $64.6 billion in 2023. Lactobacillus and Bifidobacteria are the most commonly used probiotics in the infant formulas. Probiotics are extremely beneficial for the gut health. Various factors disrupt the microflora of gastrointestinal tract of infants and cause various GI infections and diseases. Methods: Previous articles have been studied to develop this review article about a broad spectrum of pediatric disorders treated with probiotics. Probiotics are helpful in the prevention of irritable bowel syndrome, constipation, diarrhoea, gastrointestinal reflux disease, inflammatory bowel disease, acute gastroenteritis, infantile colic and necrotizing enterocolitis. Different types of probiotic mixtures and probiotic bacteria are utilized in the treatment of GI diseases. Probiotics have also proved its effectiveness in the treatment of gastrointestinal conditions. Conclusion: Efforts to improve human health are concentrating on methods for modifying the indigenous microflora using live microorganisms, now referred to as “probiotics”. The probiotic market is expanding and is expected to rise to $64.6bn by the year 2023. Probiotics are now added to a variety of food products such as cereals, fruit juices and milk-based product

References

Santacroce L, Charitos IA, Bottalico L. A successful history: probiotics and their potential as antimicrobials. Expert Review of Anti-Infective Therapy 2019 Aug; 17(8):635-645. doi: 10.1080/14787210.2019.1645597.

Sharma G and Im SH. Probiotics as a Potential Immunomodulating Pharmabiotics in Allergic Diseases: Current Status and Future Prospects. Allergy, Asthma & Immunology Research Frontiers in Microbiology 2018 Nov; 10(6):575-590. doi: 10.4168/aair.2018.10.6.575.

Wang Y, Jiang Y, Deng Y, Yi C, Wang Y, Ding M, et al. Probiotic Supplements: Hope or Hype? 2020 Feb; 11:160. doi: 10.3389/fmicb.2020.00160.

Dey G. Non-dairy Probiotic Foods: Innovations and market trends. In Innovations in technologies for fermented food and beverage industries 2018 (pp. 159-173). Springer, Cham.

Day RL, Harper AJ, Woods RM, Davies OG, Heaney LM. Probiotics: current landscape and future horizons. Future Science OA. 2019 May; 5(4): FSO391. doi: 10.4155/fsoa-2019-0004.

World Health Organization. Malnutrition. Key facts. World Health Organization. 2018:1-7.

Reid G. Probiotics: definition, scope and mechanisms of action. Best practice & research. Clinical gastroenterology. 2016 Feb; 30(1):17-25. doi: 10.1016/j.bpg.2015.12.001.

Wang X, Zhang P, Zhang X. Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity. Molecules. 2021 Oct; 26(19):6076. doi: 10.3390/molecules26196076.

Monteagudo-Mera A, Rastall RA, Gibson GR, Charalampopoulos D, Chatzifragkou A. Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Applied Microbiology and Biotechnology. 2019 Aug; 103(16):6463-6472. doi: 10.1007/s00253-019-09978-7.

Khaneghah AM, Abhari K, Eş I, Soares MB, Oliveira RB, Hosseini H, et al. Interactions between probiotics and pathogenic microorganisms in hosts and foods: A review. Trends in Food Science & Technology. 2020 Jan; 95:205-18.

Ayichew T, Belete A, Alebachew T, Tsehaye H, Berhanu H, Minwuyelet A. Bacterial probiotics their importances and limitations: a review. Journal of nutritional science 2017; 4(2):202.

Depoorter L and Vandenplas Y. Probiotics in Pediatrics. A Review and Practical Guide. Nutrients. 2021 Jun; 13(7):2176. doi: 10.3390/nu13072176.

Ford AC, Sperber AD, Corsetti M, Camilleri M. Irritable bowel syndrome. Lancet. 2020 Nov; 396(10263):1675-1688. doi: 10.1016/S0140-6736(20)31548-8.

Hojsak I. Probiotics in functional gastrointestinal disorders. Probiotics and Child Gastrointestinal Health. 2018; 121-37.

Capozza M, Laforgia N, Rizzo V, Salvatore S, Guandalini S, Baldassarre M. Probiotics and Functional Gastrointestinal Disorders in Pediatric Age: A Narrative Review. Frontiers in Pediatrics. 2022 Feb; 10:805466. doi: 10.3389/fped.2022.805466.

Dimidi E, Mark Scott S, Whelan K. Probiotics and constipation: mechanisms of action, evidence for effectiveness and utilisation by patients and healthcare professionals. Proceedings of the Nutrition Society 2020 Feb; 79(1):147-157. doi: 10.1017/S0029665119000934.

Cheng J and Ouwehand AC. Gastroesophageal Reflux Disease and Probiotics: A Systematic Review. Nutrients. 2020 Jan; 12(1):132. doi: 10.3390/nu12010132.

Przerwa F, Kukowka A, Kotrych K, Uzar I. Probiotics in the treatment of gastrointestinal diseases. Herba Polonica. 2021; 67(2).

Szajewska H. What are the indications for using probiotics in children? Arch Dis Child. 2016 Apr; 101(4):398-403. doi: 10.1136/archdischild-2015-308656.

Sansotta N, Peroni DG, Romano S, Rugiano A, Vuilleumier P, Baviera G; Italian Society of Pediatric Allergy, Immunology (SIAIP), Microbiota Committee, Italy. The good bugs: the use of probiotics in pediatrics. Current Opinion in Pediatrics 2019 Oct; 31(5):661-669. doi: 10.1097/MOP.0000000000000808.

AlOmran IA, Al-Haider FS, Awthah M, Aldail AY. An Overview on Diagnosis and Management of Gastroenteritis in Primary Health Care Center. 2020; 9(4):18-20.

Szajewska H, Guarino A, Hojsak I, Indrio F, Kolacek S, Orel R, et al. Working Group on Probiotics and Prebiotics of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition. Use of Probiotics for the Management of Acute Gastroenteritis in Children: An Update. Journal of Pediatric Gastroenterology and Nutrition 2020 Aug; 71(2):261-269. doi: 10.1097/MPG.0000000000002751.

Frej-Mądrzak M, Jeziorek M, Sarowska J, Jama-Kmiecik A, Choroszy-Król I. The role of probiotics and prebiotics in the proper functioning of gut microbiota and the treatment of diseases caused by gut microbiota dysbiosis. Nutrition, Obesity & Metabolic Surgery.;7(1):9-15.

Ong TG, Gordon M, Banks SS, Thomas MR, Akobeng AK. Probiotics to prevent infantile colic. Cochrane Database of Systematic Reviews 2019 Mar; 3(3):CD012473. doi: 10.1002/14651858.CD012473.pub2.

Pärtty A, Rautava S, Kalliomäki M. Probiotics on Pediatric Functional Gastrointestinal Disorders. Nutrients. 2018 Nov; 10(12):1836. doi: 10.3390/nu10121836.

Patel RM and Underwood MA. Probiotics and necrotizing enterocolitis. Seminars in Pediatric Surgery 2018 Feb; 27(1):39-46. doi: 10.1053/j.sempedsurg.2017.11.008.

Downloads

Published

2022-09-30
CITATION
DOI: 10.54393/pbmj.v5i9.786
Published: 2022-09-30

How to Cite

Fatima, A., & Khan, S. . (2022). Utilization of Probiotics in Treatment of Gastrointestinal Infections among Children: Probiotics in Treatment of Gastrointestinal Infections among Children. Pakistan BioMedical Journal, 5(9), 07–11. https://doi.org/10.54393/pbmj.v5i9.786

Issue

Section

Review Article

Plaudit