Comparative Study of Hematological Profile Variation in Three Trimesters of Pregnancy: Study of Hematological Profile Variation in Pregnancy

Madiha  Iqbal; Anam  Farzand; Ijaz  Ahmad; Sidra  Iqbal; Azka  Mubeen

doi:10.54393/pbmj.v5i10.807

Authors

Madiha Iqbal Deparment of Allied Health Sciences, Superior University, Lahore, Pakistan
Anam Farzand Deparment of Allied Health Sciences, Superior University, Lahore, Pakistan
Ijaz Ahmad Deparment of Allied Health Sciences, Superior University, Lahore, Pakistan
Sidra Iqbal Deparment of Allied Health Sciences, Superior University, Lahore, Pakistan
Azka Mubeen Deparment of Allied Health Sciences, Superior University, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i10.807

Keywords:

Lymphocyte, Eosinophils, MCH, MCHC, Pregnancy, Trimester, CBC

Abstract

Pregnancy or gestation is a physiological condition in which various physiological changes occur. Although pregnancy is a normal phenomenon, several hematological parameters are varied to fulfill the needs of the developing fetus. Sometimes pregnancy becomes complicated due to these changes. Objective: To determine the changes in the hematological profile of healthy pregnant females. Methods: 180 females aged 21 to 34 participated in this study and were placed in a first, second, and third group according to their trimesters, while the fourth group was the control. Each contained 45 females. These women were examined for 12 hematological parameters. Results: When compared with control, it was observed that Hb and RBCs (p-value < 0.05) were lower than control while WBCs (p-value ≤ 0.03) were increased. MCV, MCH and MCHC (p-value < 0.05) showed discontinuous variations along three trimesters. Increase in platelets and neutrophils while a decrease in monocytes, eosinophils, and lymphocytes was observed (p-value <0.02). Conclusions: This study reported several changes in pregnant females' hematological parameters, which helped determine the reference ranges for these parameters. Moreover, pregnant women should have a balanced diet, and their hematological profile should be regularly monitored

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