Platelets and D-dimer as the Biomarkers for COVID-19: Platelets and D-dimers as Biomarkers for  COVID-19

Sabrina Rashid; Aqsa  Zulfiqar; Ayesha  Abdul Sattar; Muhammad  Rizwan; Waqar  Ali; Arham  Ilyas

doi:10.54393/pbmj.v4i2.92

Authors

Sabrina Rashid University institute of medical laboratory technology (UIMLT), University of Lahore
Aqsa Zulfiqar University institute of medical laboratory technology (UIMLT), University of Lahore
Ayesha Abdul Sattar University institute of medical laboratory technology (UIMLT), University of Lahore
Muhammad Rizwan University institute of medical laboratory technology (UIMLT), University of Lahore
Waqar Ali University institute of medical laboratory technology (UIMLT), University of Lahore
Arham Ilyas University institute of medical laboratory technology (UIMLT), University of Lahore

DOI:

https://doi.org/10.54393/pbmj.v4i2.92

Abstract

COVID-19, a highly contagious and rapidly spreading viral infection caused by the new corona virus SARS-COV-2, was first identified in China. On March11th, 2020 World Health Organization announced it a pandemic. The novel infection which is still being studied has a wide range of severity, ranging from no symptoms to severe pneumonia that can lead to death Objective: To find correlation between D-Dimer and platelets count with the severity of the disease Methods: It was a cross sectional study. The duration of the study was 6 months from November, 2020 to May 2021. The study was conducted in University Institute of Medical Laboratory Technology (UIMLT), University of Lahore. Data of 101 COVID-19 positive patients was taken from Shaukat Khanum Hospital, Farooq Hospital & University of Lahore Teaching Hospital (UOL), Lahore. Hematological and biochemical parameters such as Complete blood count (CBC), D-Dimer, Lactate Dehydrogenase (LDH), Platelet count (PLT) and Ferritin levels were observed. The data was analyzed using Statistical Package for Social Sciences (SPSS) Version 21.0. P-value less than and equal to 0.05 was taken as significant Results: Platelet count was decreased in severe patients of COVID-19 and was statisticallysignificant (P-value = 0.004) LDH, D-dimer, and Ferritin were increased with severity of disease and they were also statistically significant (P-value 0.005, 0.000. 0.027) respectively Conclusions:The platelet count, D-Dimer, LDH and Ferritin levels could act as the biomarker to determine the severity in COVID-19 infection

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