Intake of Anti-Epileptic Drugs and their Influences on Sexual Dysfunctions: Anti-epileptic Drugs in Sexual Dysfunctions

Roheela  Yasmeen; Nida  Mobeen; Muhammad Amjad  Khan; Irfan  Aslam; Samia  Chaudhry

doi:10.52229/pbmj.v3i2.15

Authors

Roheela Yasmeen Lahore Garrison University, Phase VI, Sector C DHA Lahore
Nida Mobeen Lahore Garrison University, Phase VI, Sector C DHA Lahore
Muhammad Amjad Khan Lahore Garrison University, Phase VI, Sector C DHA Lahore
Irfan Aslam Lahore Garrison University, Phase VI, Sector C DHA Lahore
Samia Chaudhry Services Institute of Medical Sciences, Lahore

DOI:

https://doi.org/10.52229/pbmj.v3i2.15

Abstract

Epilepsy which is also called seizures disorder is an uncontrolled action of the central nervous system. It is not a single disease but a set of neurological disorders. Actually in this situation, the brain does not receive a precise signal and as a result an abnormal condition is produced that is usually involuntary in action. In this review, we aimed to focus on the relationship of anti-epileptic drugs with sexual dysfunction and adaptation of better remedies that improve a patient’s family life. Sexual dysfunction is a common comorbidity in people with epilepsy which badly affects their quality of life. Sexual dysfunction is caused by different factors like psychiatric problems, anti-epileptic drugs (AEDs) and social factors etc. Sexual dysfunctions include ejaculatory failure, lessen libido, penile erection in men and irregular menstrual cycle in women. Common drugs such as Topiramate, Gabapentin (GBP), Valproate (VA), Carbamazepine (CBZ), Olanzapine (OL) and Risperidone (RTG) that are in practice to treat epilepsy usually produced adverse effect on sexual dysfunction. Even though a lot of studies have been carried out to control sexual dysfunction in epilepsy’s patient, but still research is going on. Medicine such as Cyproheptadine, Mianserin, Buspirone, Yohimbine were found better to treat epilepsy with minimum side effects of sexual dysfunction. Moreover, it is also seen that certain vasodilators, folate , and vitamin supplements are effective in improving the quality of life.

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