Antioxidants Activity Assessment and Utilization of Banana Peels to Attenuate the Diabetes Mellitus

Antioxidants Activity of Banana Peels against Diabetes Mellitus


  • Bakhtawar Zahid University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore-Lahore, Pakistan
  • Tabussam Tufail University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore-Lahore, Pakistan
  • Muhammad Imran Department of Food Science and Technology, University of Narowal-Pakistan
  • Hafiz Shehzad Muzammil National Institute of Food Science and Technology University of Agriculture Faisalabad
  • Tahira Batool Qaisrani Department of Agricultural Engineering and Technology, Ghazi University, Dera Ghazi Khan
  • Syeda Zil-e-huma Consultant Nutritionist at Fatima Memorial Hospital Shadman Lahore
  • Khurram Shehzad Department of Eastern Medicine, Faculty of Allied health sciences, GCUF Faisalabad
  • Muhammad Junaid Anwar Institute of Food Science and Nutrition, Bahauddin Zakariya University Multan, Pakistan
  • Samia Chaudhry Services institute of Medical Sciences, Lahore, Pakistan



Antioxidant activity, Banana, Peels, Diabetes Mellitus


Diabetes is the primary metabolic disorder listed among the top 10 death-causing diseases. The complete cure of diabetes is impossible, but the prevention and maintenance of glucose levels can reduce the diabetes severity. Objectives: To utilize the banana peel extracts to evaluate their antioxidant attributes and capability to attenuate diabetes. Methods: The antioxidant properties were assessed by measuring the DPPH, total phenolic contents (TPC), and total flavonoid contents (TFC) in ethanol, methanol, and acetone solutions. Moreover, the renal functional tests (Serum creatinine, serum urea, and BUN) and liver function tests (ALT, ASP, Serum Albumin, and total proteins) were also conducted during the 21 days experimental study in diabetes-induced (via Streptozotocin: 350 mg/kg) male Albino Wister rats. Results: The results indicated that the DPPH, TPC, and TFC contents were higher in methanol solution, i.e., 74.20±0.98%, 54.78±0.69mg GAE/g, and 39.48±0.37mg GAE/g respectively. Moreover, the results indicated that the unripe, ripe, and overripe significantly reduced liver and renal function parameters in diabetic rats. Conclusions: Banana peels have prominent potential to prevent diabetes-linked variables due to their higher antioxidant activity.


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DOI: 10.54393/pbmj.v5i7.656
Published: 2022-07-31

How to Cite

Zahid, B. ., Tufail, T., Imran, M. ., Shehzad Muzammil, H. ., Batool Qaisrani, T. ., Zil-e-huma, S. ., Shehzad, K. ., Junaid Anwar, M., & Chaudhry, S. . (2022). Antioxidants Activity Assessment and Utilization of Banana Peels to Attenuate the Diabetes Mellitus : Antioxidants Activity of Banana Peels against Diabetes Mellitus. Pakistan BioMedical Journal, 5(7), 327–333.



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