Prevalence and Risk Factors of hepatitis B and C infections in general population of Tehsil Arifwala
Hepatitis B and C Infections in General Population
DOI:
https://doi.org/10.54393/pbmj.v5i6.526Keywords:
Prevalence, Hepatitis B virus, Hepatitis C virus, Risk FactorsAbstract
According to the WHO, over 350 and 250 million individuals have been estimated as chronic carriers of HBV and HCV, worldwide. About 1.34 million deaths are attributed to HBV and HCV, globally. Objective: To estimate the seroprevalence of HBV and HCV-related hepatitis. Methods: For this purpose, a population of 300 individuals was screened for HBsAg and Anti-HCV antibodies. Data were collected from tested individuals included their age, gender, occupation. Prevalence of HBV and HCV was found at 10% and 14% respectively. Co-infection of both pathogens was observed in 1.33% of individuals. Male (18%) were more infected with these viruses as compared to females (6%). The highest percentage (75%) of HBV/HCV was in adult patients of age between 31-50 years. The various risk factor associated with the spread of viral hepatitis were also considered for a better understanding of the routes of spread of these viral infections. Results: Out of 300 screened individuals, 21% had a history of going through any dental procedure, followed by 17% with needle stick injuries. Only 7.6% of persons had a history of any blood transfusion. Conducting such type of seroprevalence studies can help the administration and health care authorities to take necessary control measures to minimize the chances of acquiring these infections by eliminating risk factors. Conclusion: Further, these surveillance studies can also play a significant role in the launch of vaccination programs in areas of high prevalence.
References
Ahmed, M. Z., Shahzad, H., Rao, T., Ali, A., & Samad, N. (2020). Seroprevalence of Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV) In District Vehari, Pakistan. Journal of the College of Physicians and Surgeons Pakistan, 30(5), 550-551.
Aljarbou, A. N. (2013). The Emergent Concern of Hepatitis B globally with special attention to Kingdom of Saudi Arabia. Int J Health Sci (Qassim), 7(3), 333-340. doi: 10.12816/0006062
Bigna, J. J., Amougou, M. A., Asangbeh, S. L., Kenne, A. M., & Nansseu, J. R. (2017). Seroprevalence of hepatitis C virus infection in Cameroon: a systematic review and meta-analysis. BMJ Open, 7(8).
Channer, M. S., Akram, A., & Saleem, M. A. (2017). Seroprevalence of Heaptitis-C carriers among children between 6 months to 15 years of age in Dera Ghazi Khan. Journal of University Medical & Dental College, 8(2), 53-56.
Chen, C.-L., Yang, J.-Y., Lin, S.-F., Sun, C.-A., Bai, C.-H., You, S.-L., . . . Chen, D.-S. (2015). Slow decline of hepatitis B burden in general population: Results from a population-based survey and longitudinal follow-up study in Taiwan. Journal of Hepatology, 63(2), 354-363.
Di Poto, C., He, S., Varghese, R. S., Zhao, Y., Ferrarini, A., Su, S., . . . Rangnekar, A. S. (2018). Identification of race-associated metabolite biomarkers for hepatocellular carcinoma in patients with liver cirrhosis and hepatitis C virus infection. PLoS One, 13(3), e0192748.
El Khoury, A., Klimack, W., Wallace, C., & Razavi, H. (2012). Economic burden of hepatitis C‐associated diseases in the United States. Journal of viral hepatitis, 19(3), 153-160.
Haider, J., Lufullah, G., Nazli, R., Akhtar, T., & Shah, A. (2017). Screening of adult dental patients visiting Khyber College of Dentistry, Peshawar for HBV and HCV infections and identifying the associated risk factors. Pakistan Journal of Medical Sciences, 33(3), 615.
Hussein, N. R., Haj, S. M., Almizori, L. A., & Taha, A. A. (2017). The prevalence of hepatitis B and C viruses among blood donors attending blood bank in Duhok, Kurdistan region, Iraq. International Journal of Infection, 4(1), e39008.
Hyun, M., Lee, Y. S., Kim, J. H., Je, J., Yoo, Y., Yeon, J. E., & Byun, K. S. (2017). Systematic review with meta‐analysis: the efficacy and safety of tenofovir to prevent mother‐to‐child transmission of hepatitis B virus. Alimentary pharmacology & therapeutics, 45(12), 1493-1505.
Ilyas, M., & Ahmad, I. (2014). Chemiluminescent microparticle immunoassay based detection and prevalence of HCV infection in district Peshawar Pakistan. Virology journal, 11(1), 127.
Kadelka, S., Dahari, H., & Ciupe, S. M. (2021). Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection. Scientific Reports, 11(1), 1-16.
Khan, M., Kalsoom, F., Batool, F., Kazmi, A., Zahra Qua, B. M., Ali, R., . . . Iqbal Hafiz, M. (2020). Undiagnosed Hepatitis B and C Virus Infection at a Teaching Hospital in Rawalpindi. Journal of Pure and Applied Microbiology, 14(2), 1279-1286.
Khan, M., Khalid, M., Ayub, N., & Javed, M. (2004). Seroprevalence and risk factors of Hepatitis C virus (HCV) in Mardan, NWFP: A hospital based study. Rawal Medical Journal, 29(2), 57-60.
Muhamad, N. A., Ghani, R. M. A., Mutalip, M. H. A., Muhammad, E. N., Haris, H. M., Zain, R. M., . . . Ismail, N. (2020). Seroprevalence of hepatitis B virus and hepatitis C virus infection among Malaysian population. Scientific Reports, 10(1), 1-11.
Nabih, H. K. (2020). The significance of HCV viral load in the incidence of HCC: a correlation between Mir-122 and CCL2. Journal of gastrointestinal cancer, 51(2), 412-417.
Organization, W. H. (2017). Global hepatitis report 2017: World Health Organization.
Ozakyol, A. (2017). Global epidemiology of hepatocellular carcinoma (HCC epidemiology). Journal of gastrointestinal cancer, 48(3), 238-240.
Papastergiou, V., Lombardi, R., MacDonald, D., & Tsochatzis, E. A. (2015). Global epidemiology of hepatitis B virus (HBV) infection. Current hepatology reports, 14(3), 171-178.
Rawat, N., Mathur, N., Rawat, K., Mathur, M., Chauhan, N., Kakkar, R., & Tinna, R. (2017). Prevalence of hepatitis B, hepatitis C and human immunodeficiency virus infection among hemodialysis patients in a tertiary health care center of Western. International Journal of Medical Science and Public Health, 6(4), 724-727.
Tao, J., Zhang, W., Yue, H., Zhu, G., Wu, W., Gong, W., . . . Zhao, H. (2019). Prevalence of Hepatitis B Virus Infection in Shenzhen, China, 2015–2018. Scientific Reports, 9(1), 1-9.
Te, H. S., & Jensen, D. M. (2010). Epidemiology of hepatitis B and C viruses: a global overview. Clinics in liver disease, 14(1), 1-21.
Torres, H. A., Shigle, T. L., Hammoudi, N., Link, J. T., Samaniego, F., Kaseb, A., & Mallet, V. (2017). The oncologic burden of hepatitis C virus infection: a clinical perspective. CA: a cancer journal for clinicians, 67(5), 411-431.
Tu, T., Block, J. M., Wang, S., Cohen, C., & Douglas, M. W. (2020). The lived experience of chronic hepatitis B: a broader view of its impacts and why we need a cure. Viruses, 12(5), 515.
WHO. (2017). Global hepatitis report 2017: World Health Organization.
Wong, M. C., Huang, J. L., George, J., Huang, J., Leung, C., Eslam, M., . . . Ng, S. C. (2019). The changing epidemiology of liver diseases in the Asia–Pacific region. Nature reviews Gastroenterology & hepatology, 16(1), 57-73.
Zaidi, A., Tariq, W. Z., Haider, K., Ali, L., Sattar, A., Faqeer, F., & Rehman, S. (2004). Seroprevalence of hepatitis B, C and HIV in healthy blood donors in Northwest of Pakistan. Pak J Pathol, 15(1), 11-16
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