Anatomical Sites OF Superficial Basal   Cell Cancers Demonstrate Higher Rates of Mixed Histology: Anatomical Sites of Superficial Basal Cell Cancers

Zahid  Sarfaraz Khan; Asim  Muhammad; Muhammad  Ataullah; Syeda Gulrukh  Saba Shah; Tehmina  Naushin; Hina  Mir; Nabiha  Naeem; Ziyad  Ahmad; Sudhair  Abbas Bangash; Irfan  Ullah

doi:10.54393/pbmj.v5i5.451

Authors

Zahid Sarfaraz Khan Department of anatomy, Khyber Girls Medical College, Peshawar
Asim Muhammad Department of Pathology, KMU Institute of Medical Sciences, Kohat
Muhammad Ataullah Department of Anatomy, Pak International Medical College, Peshawar
Syeda Gulrukh Saba Shah Anatomy Department and Modular Coordinator DME, Kabir Medical College, Gandara University, Peshawar
Tehmina Naushin Department of Oral Pathology, Peshawar Dental College and Hospital, Warsak road Peshawar
Hina Mir Department of Biochemistry, Shaheed Benazir Bhutto Women University, Peshawar, Pakistan
Nabiha Naeem Department of Life Sciences, School of Science, University of Management and Technology (UMT), Lahore, Pakistan
Ziyad Ahmad Department of Zoology, Kohat University of Science and Technology, Kohat
Sudhair Abbas Bangash Faculty of Life Science, Department of Pharmacy, Sarhad University of Science and Information Technology, Peshawar, Pakistan
Irfan Ullah Department of Life Sciences, School of Science, University of Management and Technology (UMT), Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i5.451

Keywords:

Basal Cell Cancer, Histology, Carcinoma, Peshawar, Immunocompromised

Abstract

Historically, "aggressive" histologic subsets (HSs) of basal cell carcinoma (BCC) seem to be more likely to statistically exhibit Subclinical extension and require more phases during Mohs micrographic surgery (MMS) and consequently larger margins upon excision. The "Mohs Suitable Use Criteria (MAUC)" for the most appropriate therapy of superficial basal cell carcinoma. Objective: To evaluate if aggressive subtypes of superficial Basal Cell Carcinoma are common among healthy, immunocompromised patients and high-risk anatomical sites. Methods: The study was carried out in Khyber Teaching Hospital Peshawar, from November 2021-march to 2022, A total of 100 Mohs surgeries on superficial basal cell carcinoma were performed. Under light microscope slides were examined for any pattern of histology besides superficial basal cell carcinoma for statistical analysis MAU anatomical site healthy individuals and immunocompromised patients were grouped accordingly Results: Among health and immunocompromised individuals’ zone H and zone L were significantly increased in mixed histology. While in healthy individuals’ the association between L Zone and M zone was incredibly significant but in immunocompromised was not significant Conclusions: The mixed histology of SBCC was higher in the head and neck region. Researchers say that the MAUC scoring technique for SBCC is supported by a high incidence in SBCC of the head and neck.

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