Assessment of Knowledge Regarding Hepatitis C Transmission, Treatment, and Vaccination among Health Care Providers: Assessment of Knowledge Regarding Hepatitis C Transmission, Treatment, and Vaccination among Health Care Providers

Urwa  Nasir; Akash  John; Nasir  Ameen; . Sehrish; Amina Sharif  Bhatti

doi:10.54393/pbmj.v5i4.376

Authors

Urwa Nasir University Institute of Radiological Sciences and Medical Imaging, University of Lahore, Gujrat Campus
Akash John University Institute of Radiological Sciences and Medical Imaging, University of Lahore, Gujrat Campus
Nasir Ameen Butt Eye Hospital, Wazirabad
. Sehrish University Institute of Radiological Sciences and Medical Imaging, University of Lahore, Gujrat Campus
Amina Sharif Bhatti University Institute of Radiological Sciences and Medical Imaging, University of Lahore, Gujrat Campus

DOI:

https://doi.org/10.54393/pbmj.v5i4.376

Keywords:

Hepatitis C, Knowledge, Transmission, Vaccination, Treatment

Abstract

Hepatitis C virus (HCV) is a disease transmitted through contaminated blood and can also be transferred from mother to child during delivery. This inflammatory disease causes everlasting damage to the liver leading to death. Objective: To assess the knowledge regarding Hepatitis C transmission, treatment, and vaccination among health care providers. Methods: It is a cross-sectional descriptive study conducted in tehsil Wazirabad, district Gujranwala. The study included medical and paramedical staff of 2 health care setups: Iqra Medical Complex and Butt Eye Hospital. The 260 participants were included as per convenience after informed consent. Data were collected from January 2021 to August 2021 using a validated self-administered questionnaire. Data was entered and analyzed on SPSS version 21. The responses of the participants were recorded on 5 points Likert scale and frequencies and percentages were mentioned as a response. Results: The mean age of respondents was 28.3 ± 5.6 years with minimum and maximum ages as 20 and 45years. The participants included males 176 (67.7%) and females 84 (32.3%). The participants had sufficient knowledge about Hepatitis C transmission, symptoms, and effects on the liver. But respondents 30 (11.5%) strongly disagreed and 60 (23%) disagreed that Hepatitis C can be transferred from mother to child. The majority of the respondents 138 (53.1%) strongly disagreed with 50 (19.2%) that hepatitis can survive at room temperature. Moreover, the maximum number of respondents such as 160 (61.5%) strongly disagreed about proper updated knowledge of the treatment. Conclusions: In conclusion, the respondents have sufficient knowledge about Hepatitis C symptoms, transmission, and its long-term effects on the liver. They were unaware of HCV survival at room temperature and its transmission from mother to child at the time of birth. Moreover, the staff members also lack the knowledge of updated treatment plans.

References

Yeung C-Y, Lee H-C, Chan W-T, Jiang C-B, Chang S-W, et al. Vertical transmission of hepatitis C virus: Current knowledge and perspectives. World journal of hepatology. 2014,6(9):643. doi.org/10.4254/wjh.v6.i9.643

Samuel ST, Martinez AD, Chen Y, Markatou M, Talal AH. Hepatitis C virus knowledge improves hepatitis C virus screening practices among primary care physicians. World Journal of Hepatology. 2018,10(2):319. doi.org/10.4254/wjh.v10.i2.319

Setia S, Gambhir R, Kapoor V, Jindal G, Garg S. attitudes and awareness regarding Hepatitis B and Hepatitis C Amongst Health. care Workers of a Tertiary Hospital in India. Annals of medical and health sciences research. 2013,3(3):551-558. doi.org/10.4103/2141-9248.122105

Joukar F, Mansour-Ghanaei F, Naghipour MR, Hasandokht T. Nurses’ knowledge toward hepatitis B and hepatitis C in Guilan, Iran. The open nursing journal. 2017,11:34. doi.org/10.2174/1874434601711010034

Lavanchy D. Evolving epidemiology of hepatitis C virus. Clinical Microbiology and Infection. 2011,17(2):107-115. doi.org/10.1111/j.1469-0691.2010.03432.

John A, Rana MS, Hanif A, Faridi TA, Noor S, et al. Knowledge, Attitudes and Practices of Male Transgenders in Transmission of Human Immunodeficiency Virus in Lahore, Pakistan: Male Transgenders in Transmission of HIV. Pakistan BioMedical Journal. 2021,4(1). doi.org/10.54393/pbmj.v4i1.84

Rockstroh JK, Spengler U. HIV and hepatitis C virus co-infection. The Lancet infectious diseases. 2004,4(7):437-444. doi.org/10.1016/S1473-3099(04)01059-X

Alter MJ. Epidemiology of hepatitis C virus infection. World journal of gastroenterology: WJG. 2007,13(17):2436. doi.org/10.3748/wjg.v13.i17.2436

Arshad A, Ashfaq UA. Epidemiology of hepatitis C infection in Pakistan: current estimate and major risk factors. Critical Reviews™ in Eukaryotic Gene Expression. 2017,27(1). doi.org/10.1615/CritRevEukaryotGeneExpr.2017018953

Younossi ZM, Stepanova M, Sulkowski M, Naggie S, Puoti M, et al. Sofosbuvir and ribavirin for treatment of chronic hepatitis C in patients coinfected with hepatitis C virus and HIV: the impact on patient-reported outcomes. The Journal of infectious diseases. 2015,212(3):367-377. doi.org/10.1093/infdis/jiv005

Zibbell JE, Iqbal K, Patel RC, Suryaprasad A, Sanders KJ, et al. Increases in hepatitis C virus infection related to injection drug use among persons aged≤ 30 years—Kentucky, Tennessee, Virginia, and West Virginia, 2006–2012. MMWR Morbidity and mortality weekly report. 2015,64(17):453.

Trickey A, Fraser H, Lim AG, Peacock A, Colledge S, et al. The contribution of injection drug use to hepatitis C virus transmission globally, regionally, and at country level: a modelling study. The lancet Gastroenterology & hepatology. 2019,4(6):435-444. doi.org/10.1016/S2468-1253(19)30085-8

Ryerson AB, Schillie S, Barker LK, Kupronis BA, Wester C. Vital signs: newly reported acute and chronic hepatitis C cases―United States, 2009–2018. Morbidity and Mortality Weekly Report. 2020,69(14):399. doi.org/10.15585/mmwr.mm6914a2

Zibbell JE, Asher AK, Patel RC, Kupronis B, Iqbal K, et al. Increases in acute hepatitis C virus infection related to a growing opioid epidemic and associated injection drug use, United States, 2004 to 2014. American journal of public health. 2018,108(2):175-181. doi.org/10.2105/AJPH.2017.304132

Alter MJ. Epidemiology of hepatitis C. Hepatology. 1997,26(S3):62S-5S. doi.org/10.1002/hep.510260711

Mtengezo J, Lee H, Ngoma J, Kim S, Aronowitz T, et al. Knowledge and attitudes toward HIV, hepatitis B virus, and hepatitis C virus infection among health-care workers in Malawi. Asia-Pacific journal of oncology nursing. 2016,3(4):344-51. doi.org/10.4103/2347-5625.195921

Zia R, Afridi IUK, Rafiq H, Sheikh GA, Abbas F. Magnitude of Hepatitis C Virus Infection among Asymptomatic Pakistani children. Pak J of Med & Health Sci. 2016,10(3):902-904.

Benova L, Awad SF, Abu‐Raddad LJ. Estimate of vertical transmission of Hepatitis C virus in Pakistan in 2007 and 2012 birth cohorts. Journal of viral hepatitis. 2017,24(12):1177-1183. doi.org/10.1111/jvh.12748

Sheha E, Hassan HE, Genedy ASE, Hassanine ST. Effect of educational program on mother's knowledge and practice regarding Hepatitis C Virus in rural areas. American Journal of Nursing. 2020,8(3):312-319.

Kushner T, Cohen J, Tien PC, Terrault NA. Evaluating women’s preferences for hepatitis C treatment during pregnancy. Hepatology communications. 2018,2(11):1306-1310. doi.org/10.1002/hep4.1264

Foster GR, Irving WL, Cheung MC, Walker AJ, Hudson BE, et al. Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis. Journal of hepatology. 2016,64(6):1224-1231.doi.org/10.1016/j.jhep.2016.01.029

Cabibbo G, Celsa C, Calvaruso V, Petta S, Cacciola I,et al. Direct-acting antivirals after successful treatment of early hepatocellular carcinoma improve survival in HCV-cirrhotic patients. Journal of hepatology. 2019,71(2):265-273. doi.org/10.1016/j.jhep.2019.03.027

Dibba P, Cholankeril R, Li AA, Patel M, Fayek M,et al. Hepatitis C in pregnancy. Diseases. 2018,6(2):31. doi.org/10.3390/diseases6020031

Hagan H, Pouget ER, Des Jarlais DC. A systematic review and meta-analysis of interventions to prevent hepatitis C virus infection in people who inject drugs. Journal of Infectious Diseases. 2011,204(1):74-83. doi.org/10.1093/infdis/jir196

Parlati L, Hollande C, Pol S. Treatment of hepatitis C virus infection. Clinics and Research in Hepatology and Gastroenterology. 2021,45(4):101578. doi.org/10.1016/j.clinre.2020.11.008