A Prospective Cohort Study on Suspected COVID-19 Patients undergoing Nasopharyngeal Swab PCR and HRCT

Nasopharyngeal Swab PCR and HRCT in COVID-19 Patients


  • Akash John University Institute of Radiological and Medical Imaging Sciences, The University of Lahore, Gujrat Campus
  • Tallat Anwar Faridi University Institute of Public Health, The University of Lahore
  • Kubra Samreen Medical Imaging Technologist, Sharif Medical City Hospital, Lahore
  • Anil Gill Gujranwala Institute of Medical and Emerging Sciences, Gujranwala
  • Sofia Noor Operation Theatre Technologist, District Head Quarter (DHQ Hospital), Okara
  • Neelam Iqbal Institute of Molecular Biology and Biotechnology, The University of Lahore
  • Nayab John University Institute of Physical therapy, University of Lahore, Gujrat campus




Objective:To Determine the Specificity, Accuracy and Sensitivity of HRCT in Diagnosis of Covi-19.

Methods: Prospective cohort study was done with 181 participants who were suspected for COVID-19 infection and were followed to evaluate PCR and HRCT reporting in patients with clinical symptoms.

Results: 86.8% of patients had a dry cough, followed most commonly with shortness of breath. 65 (35.9%) of patients had ground-glass opacities of haze on HRCT followed by 47 (26 %). who had consolidations present. 147 (81.2)patients had a positive PCR whereas 34 (18.7%) was negative had an HRCT that was suggestive of having COVID-19 pneumonia.

Conclusion:In conclusion clinical symptomatology, HRCT findings and PCR all should be used in a triple examination. It is concluded that a positive PCR test is very specific and used to make diagnosis for Covid-19. CT has a higher sensitivity but a lower specificity, thus helping with disease diagnosis and therapy.


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DOI: 10.54393/pbmj.v4i1.82
Published: 2021-06-25

How to Cite

John, A. ., Faridi, T. A. ., Samreen, K. ., Gill, A., Noor, S. ., Iqbal, N. ., & John, N. . (2021). A Prospective Cohort Study on Suspected COVID-19 Patients undergoing Nasopharyngeal Swab PCR and HRCT: Nasopharyngeal Swab PCR and HRCT in COVID-19 Patients. Pakistan BioMedical Journal, 4(1). https://doi.org/10.54393/pbmj.v4i1.82



Original Article


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